Xpo4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Xpo4
exportin 4
MGI:1888526

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Xpo4^em1(IMPC)Tcp/Xpo4⁺ C57BL/6NCrl-Xpo4^em1(IMPC)Tcp/Tcp	abnormal retina morphology	J:211773
Xpo4^em1(IMPC)Tcp/Xpo4⁺ C57BL/6NCrl-Xpo4^em1(IMPC)Tcp/Tcp	microphthalmia	J:211773
Xpo4^em1(IMPC)Tcp/Xpo4^em1(IMPC)Tcp C57BL/6NCrl-Xpo4^em1(IMPC)Tcp/Tcp	edema	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Xpo4^em1Gshan/Xpo4⁺ involves: C57BL/6J	abnormal hippocampus neuron morphology	J:330082
	abnormal hippocampus physiology	J:330082
	abnormal spatial reference memory	J:330082
	abnormal spatial working memory	J:330082
	abnormal testis physiology	J:330082
	absent sperm head	J:330082
	asthenozoospermia	J:330082
	coiled sperm flagellum	J:330082
	decreased neuron number	J:330082
	decreased sperm progressive motility	J:330082
	increased cell death	J:330082
	male infertility	J:330082
	oligozoospermia	J:330082
	small testis	J:330082
	teratozoospermia	J:330082
Xpo4^em1Gshan/Xpo4^em1Gshan involves: C57BL/6J	embryonic lethality prior to tooth bud stage	J:330082
Xpo4^{Gt(PT1-ATG)3EVal}/Xpo4^{Gt(PT1-ATG)3EVal} involves: 129S1/Sv * 129X1/SvJ * BALB/c	no abnormal phenotype detected	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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