H1f6 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H1f6
H1.6 linker histone, cluster member
MGI:1888530

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Acr^tm1Wen/Acr^tm1Wen H1f6^tm1Ais/H1f6^tm1Ais Tnp2^tm1Wen/Tnp2^tm1Wen involves: 129/Sv * C57BL/6J * CD-1 * SJL	no abnormal phenotype detected	J:86670
Acr^tm1Wen/Acr^tm1Wen H1f6^tm1Drab/H1f6^tm1Drab Smcp^tm1Wen/Smcp^tm1Wen involves: 129/Sv * C57BL/6J * CD-1	abnormal sperm head morphology	J:98301
	asthenozoospermia	J:98301
	impaired binding of sperm to zona pellucida	J:98301
	impaired fertilization	J:98301
	impaired sperm migration in female genital tract	J:98301
	reduced male fertility	J:98301
H1f6^tm1Drab/H1f6⁺ Smcp^tm1Wen/Smcp^tm1Wen Tnp2^tm1Wen/Tnp2^tm1Wen involves: 129 * C57BL/6J	reduced male fertility	J:98301
H1f6^tm1Drab/H1f6^tm1Drab Smcp^tm1Wen/Smcp⁺ Tnp2^tm1Wen/Tnp2^tm1Wen involves: 129 * C57BL/6J	normal reproductive system phenotype	J:98301
H1f6^tm1Drab/H1f6^tm1Drab Smcp^tm1Wen/Smcp^tm1Wen Tnp2^tm1Wen/Tnp2⁺ involves: 129 * C57BL/6J	male infertility	J:98301
H1f6^tm1Drab/H1f6^tm1Drab Smcp^tm1Wen/Smcp^tm1Wen Tnp2^tm1Wen/Tnp2^tm1Wen involves: 129 * C57BL/6J	asthenozoospermia	J:98301
	impaired fertilization	J:98301
	impaired sperm penetration of zona pellucida	J:98301
	male infertility	J:98301

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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