Icmt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Icmt
isoprenylcysteine carboxyl methyltransferase
MGI:1888594

19 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Icmt^tm1Hzo/Icmt^tm1Hzo involves: 129S/SvEv	abnormal definitive hematopoiesis	J:77742
	abnormal liver bud morphology	J:77742
	abnormal liver development	J:77742
	absent liver	J:77742
	decreased embryo size	J:77742
	delayed hepatic development	J:77742
	embryonic lethality during organogenesis, complete penetrance	J:77742
	increased forebrain apoptosis	J:77742
	increased neural tube apoptosis	J:77742
	pallor	J:77742
Icmt^tm1Mbrg/Icmt^tm1Mbrg involves: 129S4/SvJae	no abnormal phenotype detected	J:88170
Icmt^tm1Mbrg/Icmt^tm1Mbrg Tg(Mx1-cre)1Cgn/? involves: 129S4/SvJae * C57BL/6 * CBA	decreased cell proliferation	J:88170
Icmt^tm1Mbrg/Icmt^tm1Mbrg Tg(Six3-cre)69Frty/0 involves: 129 * C57BL/6 * DBA/2	abnormal electroretinogram waveform feature	J:231728
	abnormal retina neuronal layer morphology	J:231728
	abnormal vision	J:231728
	decreased a-wave amplitude	J:231728
	decreased b-wave amplitude	J:231728
	retina photoreceptor degeneration	J:231728
Icmt^tm1Sgy/Icmt^tm1Sgy Not Specified	decreased body size	J:67598
Icmt^tm1Sgy/Icmt^tm1Sgy Not Specified	embryonic lethality during organogenesis, complete penetrance	J:67598

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24