Icmt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Icmt
isoprenylcysteine carboxyl methyltransferase
MGI:1888594

19 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Icmt^tm1Hzo/Icmt^tm1Hzo involves: 129S/SvEv	abnormal definitive hematopoiesis	J:77742
	abnormal liver bud morphology	J:77742
	abnormal liver development	J:77742
	absent liver	J:77742
	decreased embryo size	J:77742
	delayed hepatic development	J:77742
	embryonic lethality during organogenesis, complete penetrance	J:77742
	increased forebrain apoptosis	J:77742
	increased neural tube apoptosis	J:77742
	pallor	J:77742
Icmt^tm1Mbrg/Icmt^tm1Mbrg involves: 129S4/SvJae	no abnormal phenotype detected	J:88170
Icmt^tm1Mbrg/Icmt^tm1Mbrg Tg(Mx1-cre)1Cgn/? involves: 129S4/SvJae * C57BL/6 * CBA	decreased cell proliferation	J:88170
Icmt^tm1Mbrg/Icmt^tm1Mbrg Tg(Six3-cre)69Frty/0 involves: 129 * C57BL/6 * DBA/2	abnormal electroretinogram waveform feature	J:231728
	abnormal retina neuronal layer morphology	J:231728
	abnormal vision	J:231728
	decreased a-wave amplitude	J:231728
	decreased b-wave amplitude	J:231728
	retina photoreceptor degeneration	J:231728
Icmt^tm1Sgy/Icmt^tm1Sgy Not Specified	decreased body size	J:67598
Icmt^tm1Sgy/Icmt^tm1Sgy Not Specified	embryonic lethality during organogenesis, complete penetrance	J:67598

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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