Extl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Extl1
exostosin-like glycosyltransferase 1
MGI:1888742

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Extl1^em1(IMPC)J/Extl1^em1(IMPC)J C57BL/6NJ-Extl1^em1(IMPC)J/Mmjax	increased total body fat amount	J:211773
Extl1^em1Caox/Extl1^em1Caox Tg(Itgax-cre)1-1Reiz/0 involves: C57BL/6 * CBA	abnormal dendritic cell chemotaxis	J:333437
	abnormal dendritic cell migration	J:333437
	abnormal dendritic cell physiology	J:333437
	abnormal kidney morphology	J:333437
	abnormal regulatory T cell morphology	J:333437
	chronic inflammation	J:333437
	decreased acute inflammation	J:333437
	decreased body weight	J:333437
	decreased dendritic cell number	J:333437
	decreased T helper 1 cell number	J:333437
	enlarged lymph nodes	J:333437
	enlarged spleen	J:333437
	normal immune system phenotype	J:333437
	increased B cell number	J:333437
	increased circulating interleukin-6 level	J:333437
	increased circulating interleukin-17 level	J:333437
	increased circulating tumor necrosis factor level	J:333437
	increased IgG level	J:333437
	increased immunoglobulin level	J:333437
	increased interleukin-6 secretion	J:333437
	increased Ly6C high monocyte number	J:333437
	increased susceptibility to autoimmune disorder	J:333437
	increased susceptibility to bacterial infection induced morbidity/mortality	J:333437
	increased T cell number	J:333437
	increased T-helper 17 cell number	J:333437

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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