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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cyp2c23
cytochrome P450, family 2, subfamily c, polypeptide 23
MGI:1888897
15 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cyp2c23Gt(OST85045)Lex/Cyp2c23Gt(OST85045)Lex
129-Cyp2c23Gt(OST85045)Lex 		abnormal kidney physiology J:204734
abnormal lung endothelial cell physiology J:207597
decreased circulating aldosterone level J:204734
decreased incidence of induced tumors J:207597
decreased lung endothelial cell proliferation J:207597
decreased urine sodium level J:204734
increased circulating sodium level J:204734
increased susceptibility to weight gain J:204734
salt-sensitive hypertension J:204734
Cyp2c23tm1.1Jhc/Cyp2c23tm1.1Jhc
Tg(Hoxb7-cre)13Amc/0
involves: C57BL/6 		abnormal kidney physiology J:213555
decreased urine sodium level J:213555
increased body weight J:213555
increased systemic arterial systolic blood pressure J:213555
Cyp2c23tm1b(EUCOMM)Hmgu/Cyp2c23tm1b(EUCOMM)Hmgu
C57BL/6N-Cyp2c23tm1b(EUCOMM)Hmgu/J 		increased circulating alkaline phosphatase level J:211773
increased circulating cholesterol level J:211773
increased grip strength J:211773
increased mean corpuscular hemoglobin J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory