Dlg3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dlg3
discs large MAGUK scaffold protein 3
MGI:1888986

16 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dlg3^{Gt(P038A02)Wrst}/Y chimera involves: 129S6/SvEvTac * C57BL/6J	abnormal forebrain development	J:160967
	caudal body truncation	J:160967
	failure of initiation of embryo turning	J:160967
Dlg3^{tm1a(EUCOMM)Wtsi}/Y C57BL/6N-Dlg3^{tm1a(EUCOMM)Wtsi}/Wtsi	increased bone mineral density	J:211773
Dlg3^tm1Grnt/Y involves: 129P2/OlaHsd * C57BL/6J	abnormal axon morphology	J:238576
	abnormal barrel cortex morphology	J:238576
	abnormal brain morphology	J:238576
	abnormal innervation	J:238576
	abnormal neocortex size	J:238576
	abnormal somatosensory cortex morphology	J:238576
	abnormal synapse morphology	J:238576
	decreased excitatory postsynaptic current amplitude	J:238576
	prolonged excitatory postsynaptic current decay time	J:238576
Dlg3^tm1Grnt/Y involves: 129P2/OlaHsd * MF1	abnormal locomotor activation	J:120078
	abnormal long-term potentiation	J:120078
	abnormal spatial learning	J:120078

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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