Angptl4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Angptl4
angiopoietin-like 4
MGI:1888999

27 phenotypes from 7 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Angptl4^{Gt(OST352973)Lex}/Angptl4^{Gt(OST352973)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal intestinal mucosa morphology	J:122968
	abnormal lipid homeostasis	J:122968
	abnormal lymphatic vessel morphology	J:122968
	abnormal mesenteric lymph node morphology	J:122968
	chylous ascites	J:122968
	decreased circulating HDL cholesterol level	J:122968
	decreased circulating VLDL cholesterol level	J:122968
	decreased triglyceride level	J:122968
	enhanced lipolysis	J:122968
	increased susceptibility to induced morbidity/mortality	J:122968
	postnatal lethality	J:122968
Angptl4^tm1Akos/Angptl4^tm1Akos involves: 129P2/OlaHsd * C57BL/6	normal adipose tissue phenotype	J:103363
	decreased circulating cholesterol level	J:103363
	decreased circulating triglyceride level	J:103363
	increased lipoprotein lipase activity	J:103363
Angptl4^{tm1b(EUCOMM)Hmgu}/Angptl4^{tm1b(EUCOMM)Hmgu} C57BL/6N-Angptl4^{tm1b(EUCOMM)Hmgu}/H	absent optic nerve	J:211773
	decreased circulating triglyceride level	J:211773
Angptl4^tm1Jig/Angptl4⁺ involves: 129/Sv * C57BL/6	decreased total body fat amount	J:93455
Angptl4^tm1Jig/Angptl4^tm1Jig involves: 129/Sv * C57BL/6	abnormal adipose tissue physiology	J:93455
Angptl4^tm1Jig/Angptl4^tm1Jig involves: 129/Sv * C57BL/6	decreased total body fat amount	J:93455
Angptl4^tm1Lex/Angptl4⁺ involves: 129S5/SvEvBrd * C57BL/6	decreased circulating triglyceride level	J:149912
Angptl4^tm1Lex/Angptl4^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal intestinal mucosa morphology	J:122968
	abnormal lymphatic vessel morphology	J:122968
	abnormal mesenteric lymph node morphology	J:122968
	chylous ascites	J:122968
	decreased circulating HDL cholesterol level	J:122968
	decreased circulating triglyceride level	J:149912
	decreased circulating VLDL cholesterol level	J:122968
	decreased triglyceride level	J:122968
	enhanced lipolysis	J:122968
	increased susceptibility to induced morbidity/mortality	J:122968
	postnatal lethality	J:122968
Angptl4^tm1Vlcg/Angptl4^tm1Vlcg Not Specified	abnormal capillary morphology	J:177790
	abnormal induced retina neovascularization	J:177790
	abnormal pericyte morphology	J:177790
	abnormal retina blood vessel morphology	J:177790
	abnormal vein morphology	J:177790
	decreased angiogenesis	J:177790
	increased vascular permeability	J:177790
	lethality throughout fetal growth and development, incomplete penetrance	J:177790
	prenatal lethality, incomplete penetrance	J:177790
Angptl4^tm2Lex/Angptl4^tm2Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased triglyceride level	J:149912

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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