Rangrf Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rangrf
RAN guanine nucleotide release factor
MGI:1889073

22 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Rangrf^tm1.1Tke/Rangrf^tm1.1Tke involves: C57BL/6	abnormal cardiac muscle tissue morphology	J:325055
	abnormal cardiovascular system physiology	J:325055
	abnormal fibroblast physiology	J:325055
	abnormal heart echocardiography feature	J:325055
	abnormal heart ventricle morphology	J:325055
	abnormal I band morphology	J:325055
	abnormal mitochondrial biogenesis	J:325055
	abnormal mitochondrial physiology	J:325055
	abnormal myocardial fiber morphology	J:325055
	abnormal sarcomere morphology	J:325055
	atrioventricular block	J:325055
	cardiac fibrosis	J:325055
	decreased cardiac muscle contractility	J:325055
	disorganized mitochondrial cristae	J:325055
	increased fibroblast proliferation	J:325055
	increased mitochondrial number	J:325055
	increased mitochondrial size	J:325055
	increased physiological sensitivity to xenobiotic	J:325055
	increased susceptibility to xenobiotic induced morbidity/mortality	J:325055
	prolonged QRS complex duration	J:325055
	ventricular premature beat	J:325055
	ventricular tachycardia	J:325055

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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