Cadm1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cadm1
cell adhesion molecule 1
MGI:1889272

37 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cadm1^{Gt(Ayu21-W34)Imeg}/Cadm1^{Gt(Ayu21-W34)Imeg} involves: C57BL/6 * CBA/JNCrlj	abnormal T cell differentiation	J:178612
	abnormal T cell receptor V(D)J recombination	J:178612
	decreased body size	J:178612
	decreased body weight	J:178612
	decreased CD4-positive, alpha-beta T cell number	J:178612
	decreased CD8-positive, alpha-beta T cell number	J:178612
	decreased fetal size	J:178612
	decreased interferon-gamma secretion	J:178612
	decreased interleukin-2 secretion	J:178612
	decreased interleukin-4 secretion	J:178612
	decreased T cell proliferation	J:178612
	increased double-positive T cell number	J:178612
Cadm1^Gt(XI486)Byg/Cadm1⁺ involves: 129P2/OlaHsd	abnormal astrocyte morphology	J:120794
	abnormal brain morphology	J:120794
	abnormal hippocampus morphology	J:120794
	abnormal neocortex morphology	J:120794
Cadm1^tm1.1Brd/Cadm1^tm1.1Brd involves: 129S7/SvEvBrd * C57BL/6	no abnormal phenotype detected	J:108386
Cadm1^tm1.2Brd/Cadm1^tm1.2Brd involves: 129S7/SvEvBrd	normal endocrine/exocrine gland phenotype	J:210552
	increased pancreatic beta cell mass	J:210552
	increased pancreatic beta cell number	J:210552
	increased pancreatic beta cell proliferation	J:210552
Cadm1^tm1.2Brd/Cadm1^tm1.2Brd involves: 129S7/SvEvBrd * C57BL/6	arrest of spermatogenesis	J:108386
	asthenozoospermia	J:108386
	male infertility	J:108386
	oligozoospermia	J:108386
	teratozoospermia	J:108386
Cadm1^{tm1a(EUCOMM)Wtsi}/Cadm1^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Cadm1^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal behavior	J:175295
	abnormal tail movements	J:175295
Cadm1^tm1Momo/Cadm1^tm1Momo involves: 129S/SvEv	abnormal spermatid morphology	J:128950
Cadm1^tm1Momo/Cadm1^tm1Momo involves: 129S/SvEv	normal nervous system phenotype	J:199632
Cadm1^tm1Momo/Cadm1^tm1Momo involves: 129S/SvEv * C57BL/6J	abnormal spermatid morphology	J:129496
	abnormal testis weight	J:129496
	arrest of spermiogenesis	J:129496
	asthenozoospermia	J:129496
	decreased male germ cell number	J:129496
	male infertility	J:129496
	oligozoospermia	J:129496
	teratozoospermia	J:129496
Cadm1^tm1Mrkm/Cadm1^tm1Mrkm involves: 129S6/SvEvTac * C57BL/6J	arrest of spermatogenesis	J:108395
	asthenozoospermia	J:108395
	decreased testis weight	J:108395
	globozoospermia	J:108395
	male infertility	J:108395
	multiflagellated sperm	J:108395
	oligozoospermia	J:108395
	short sperm flagellum	J:108395
	teratozoospermia	J:108395

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