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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
MGI:1889383
24 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ap1s2em1(IMPC)Mbp/Y
C57BL/6N-Ap1s2em1(IMPC)Mbp/MbpMmucd 		impaired pupillary reflex J:211773
Ap1s2em1(IMPC)Mbp/Ap1s2em1(IMPC)Mbp
C57BL/6N-Ap1s2em1(IMPC)Mbp/MbpMmucd 		abnormal eye morphology J:211773
abnormal retina morphology J:211773
decreased fasting circulating glucose level J:211773
increased vertical activity J:211773
microphthalmia J:211773
Ap1s2tm1Pschu/Y
involves: 129P2/OlaHsd * C57BL/6 		abnormal adipose tissue development J:216244
abnormal fat cell differentiation J:216244
abnormal interscapular fat pad morphology J:216244
decreased body weight J:216244
decreased epididymal fat pad weight J:216244
decreased subcutaneous adipose tissue amount J:216244
decreased total body fat amount J:216244
normal homeostasis/metabolism phenotype J:216244
lipodystrophy J:216244
Ap1s2tm1Pschu/Ap1s2tm1Pschu
involves: 129P2/OlaHsd * C57BL/6 		abnormal adipose tissue development J:216244
abnormal fat cell differentiation J:216244
abnormal interscapular fat pad morphology J:216244
abnormal response to novelty J:218588
abnormal synaptic vesicle clustering J:218588
abnormal synaptic vesicle morphology J:218588
abnormal synaptic vesicle number J:218588
abnormal synaptic vesicle recycling J:218588
decreased body weight J:216244
decreased locomotor activity J:218588
decreased subcutaneous adipose tissue amount J:216244
decreased total body fat amount J:216244
normal endocrine/exocrine gland phenotype J:216244
normal homeostasis/metabolism phenotype J:216244
impaired balance J:218588
impaired spatial learning J:218588
lipodystrophy J:216244
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory