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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Porcn
porcupine O-acyltransferase
MGI:1890212
83 phenotypes from 7 alleles in 16 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
PorcnGt(CSD256)Byg/Y
chimera involves: 129P2/OlaHsd 		abnormal digit morphology J:186934
abnormal embryonic tissue morphology J:160967
abnormal vas deferens morphology J:186934
abnormal ventral body wall morphology J:186934
alopecia J:186934
dermal cyst J:186934
fused phalanges J:186934
hydronephrosis J:186934
infertility J:186934
prenatal lethality J:186934
skin lesions J:186934
thin epidermis J:186934
true hermaphroditism J:186934
Porcntm1.1Jrt/Y
B6.Cg-Porcntm1.1Jrt 		no abnormal phenotype detected J:198636
Porcntm1.1Jrt/Porcn+
B6.Cg-Porcntm1.1Jrt 		no abnormal phenotype detected J:198636
Porcntm1.1Jrt/Y
involves: 129S6/SvEvTac * C57BL/6NCr * ICR 		no abnormal phenotype detected J:198636
Porcntm1.1Jrt/Porcn+
involves: 129S6/SvEvTac * C57BL/6NCr * ICR 		no abnormal phenotype detected J:198636
Porcntm1.1Jrt/Porcn+
Tg(CAG-EGFP)D4Nagy/0
Tg(Zp3-cre)3Mrt/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCr * FVB/N 		normal embryo phenotype J:198636
Porcntm1.1Jrt/Porcn+
Tg(CAG-cre)1Nagy/0
involves: 129S6/SvEvTac * C57BL/6NCr * ICR 		abnormal allantois morphology J:198636
abnormal embryo development J:198636
abnormal placenta morphology J:198636
abnormal umbilical cord morphology J:198636
normal embryo phenotype J:198636
embryonic lethality during organogenesis, complete penetrance J:198636
normal nervous system phenotype J:198636
Porcntm1.1Jrt/Porcn+
Tg(Ttr-cre)1Hadj/0
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr * CBA/J 		normal mortality/aging J:198636
Porcntm1.1Jrt/Y
Tg(CAG-cre)1Nagy/0
involves: 129S6/SvEvTac * C57BL/6NCr * ICR 		abnormal extraembryonic tissue morphology J:198636
absent amnion J:198636
absent chorion J:198636
decreased embryo size J:198636
embryonic lethality between implantation and somite formation, complete penetrance J:198636
Porcntm1.1Jrt/Y
Tg(CAG-EGFP)D4Nagy/0
Tg(Zp3-cre)3Mrt/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCr * FVB/N 		failure to gastrulate J:198636
Porcntm1.1Lcm/Y
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:173672
Porcntm1.1Lcm/Porcn+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(rx3-icre)1Mjam/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J * CD-1 		abnormal retina pigmentation J:218165
coloboma J:218165
microphthalmia J:218165
Porcntm1.1Lcm/Porcn+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal autopod morphology J:173672
abnormal hair follicle development J:173672
abnormal tail morphology J:173672
absent ulna J:173672
caudal body truncation J:173672
cleft palate J:173672
decreased body size J:173672
hairless J:173672
normal integument phenotype J:173672
omphalocele J:173672
perinatal lethality, complete penetrance J:173672
short tail J:173672
sternum hypoplasia J:173672
thin dermal layer J:173672
Porcntm1.1Lcm/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal mesoderm development J:173672
lethality throughout fetal growth and development, complete penetrance J:173672
Porcntm1.1Lcm/Y
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J * CD-1 		abnormal craniofacial development J:218165
abnormal craniofacial morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
cleft palate J:218165
coloboma J:218165
midline cleft upper lip J:218165
Porcntm1.1Lcm/Y
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(rx3-icre)1Mjam/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J * CD-1 		abnormal anterior eye segment morphology J:218165
abnormal craniofacial morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
abnormal retina pigmentation J:218165
cleft palate J:218165
coloboma J:218165
decreased cornea thickness J:218165
failure of eyelid fusion J:218165
iris hypoplasia J:218165
midline cleft upper lip J:218165
Porcntm1.1Lcm/Porcntm1.1Lcm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:173672
Porcntm1.1Lcm/Porcntm1.2Lcm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 		abnormal craniofacial morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
abnormal retina pigmentation J:218165
coloboma J:218165
failure of eyelid fusion J:218165
Porcntm1.1Lcm/Porcntm1.2Lcm
Tg(Six3-cre)69Frty/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * DBA/2 		abnormal craniofacial morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
abnormal retina pigmentation J:218165
coloboma J:218165
failure of eyelid fusion J:218165
failure of ventral body wall closure J:218165
skin hypoplasia J:218165
Porcntm1.1Lcm/Y
Tg(Msx2-cre)5Rem/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal dermal layer morphology J:173672
abnormal skin morphology J:173672
decreased autopod size J:173672
syndactyly J:173672
Porcntm1.1Lcm/Y
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL/J 		oligodactyly J:173672
short limbs J:173672
Porcntm1.1Lcm/Y
Tg(rx3-icre)1Mjam/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 		abnormal craniofacial morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
abnormal retina pigmentation J:218165
coloboma J:218165
Porcntm1.1Vdv/Porcn+
Tg(KRT14-cre)1Efu/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J 		abnormal hair growth J:186934
Porcntm1.1Vdv/Porcn+
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N 		abnormal hair growth J:186934
prenatal lethality, incomplete penetrance J:186934
Porcntm1.1Vdv/Porcn+
Hprt1tm1(CAG-cre)Mnn/Hprt1+
involves: 129S/Sv * C57BL/6J 		abnormal ventral body wall morphology J:186934
caudal body truncation J:186934
embryonic growth retardation J:186934
embryonic lethality during organogenesis, incomplete penetrance J:186934
open neural tube J:186934
prenatal lethality, complete penetrance J:186934
Porcntm1.1Vdv/Y
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N 		abnormal hair growth J:186934
prenatal lethality, incomplete penetrance J:186934
Porcntm1.1Vdv/Y
Tg(KRT14-cre)1Efu/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J 		abnormal hair follicle development J:186934
abnormal hypodermis fat layer morphology J:186934
abnormal tooth morphology J:186934
alopecia J:186934
thin skin J:186934
Porcntm1.1Vdv/Y
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J 		brachydactyly J:186934
decreased body size J:186934
decreased length of long bones J:186934
postnatal growth retardation J:186934
short limbs J:186934
syndactyly J:186934
Porcntm1.2Lcm/Porcntm1.2Lcm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * DBA/2 		abnormal craniofacial morphology J:218165
abnormal limb morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
abnormal retina pigmentation J:218165
caudal body truncation J:218165
coloboma J:218165
curly tail J:218165
failure of eyelid fusion J:218165
forelimb oligodactyly J:218165
short tail J:218165
syndactyly J:218165
Porcntm1.2Vdv/Porcn+
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N 		abnormal hair growth J:186934
embryonic lethality, incomplete penetrance J:186934
prenatal lethality, incomplete penetrance J:186934
Porcntm1.2Vdv/Y
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N 		embryonic lethality, complete penetrance J:186934
Porcntm1Vdv/Porcn+
chimera involves: 129S5/SvEvBrd * C57BL/6J 		abnormal caudal vertebrae morphology J:186934
abnormal uterine horn morphology J:186934
brachydactyly J:186934
fused phalanges J:186934
hydronephrosis J:186934
oligodactyly J:186934
Porcntm1Vdv/Y
chimera involves: 129S5/SvEvBrd * C57BL/6J 		abnormal caudal vertebrae morphology J:186934
brachydactyly J:186934
fused phalanges J:186934
hydronephrosis J:186934
oligodactyly J:186934
small testis J:186934
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory