Cdh23 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdh23
cadherin related 23 (otocadherin)
MGI:1890219

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Adgrv1^frings/Adgrv1^frings Cdh23^ahl/Cdh23^ahl involves: BUB/BnJ * CAST/EiJ	deafness	J:97534
Adgrv1^frings/Adgrv1^frings Cdh23^ahl/Cdh23^ahl involves: BUB/BnJ * MOLD/RkJ	deafness	J:97534
Atp2b2^dfw-2J/Atp2b2⁺ Cdh23^ahl/Cdh23^ahl involves: BALB/cByJ * MOLF	deafness	J:38429
	increased or absent threshold for auditory brainstem response	J:38429
Atp2b2^dfw-2J/Atp2b2⁺ Cdh23^ahl/Cdh23^ahl involves: CAST/Ei * BALB/cByJ	deafness	J:38429
	increased or absent threshold for auditory brainstem response	J:38429
	increased susceptibility to age-related hearing loss	J:38429
Cdh23^Ahl+/Cdh23^Ahl+ Tbc1d24^em4Tbf/Tbc1d24^em4Tbf B6.Cg-Cdh23^Ahl+ Tbc1d24^em4Tbf	normal hearing/vestibular/ear phenotype	J:299025
Cdh23^Ahl+/Cdh23^Ahl+ Ush2a^tm1Tili/Ush2a^tm1Tili involves: 129S4/SvJae * C57BL/6 * CAST/EiJ * CBA/CaJ	abnormal distortion product otoacoustic emission	J:118927
Cdh23^ahl/Cdh23^ahl Adgrv1^frings/Adgrv1^frings involves: BUB/BnJ * RB/1	deafness	J:97534
	increased susceptibility to age-related hearing loss	J:97534
Cdh23^ahl/Cdh23^ahl Mahl^C57BL/6J/Mahl^C57BL/6J 129S1.B6-(rs3696307-rs257098870)/Kjn	cochlear hair cell degeneration	J:241137
	increased or absent threshold for auditory brainstem response	J:241137
Cdh23^ahl/Cdh23^ahl mt-Tr^m1 either: A/J X (A/J x CAST/Ei)F1 or A/J X (CAST/Ei x A/J)F1	increased or absent threshold for auditory brainstem response	J:67312
	increased susceptibility to age-related hearing loss	J:67312
Cdh23^ahl/Cdh23^ahl mt-Tr^m2 either: NOD/LtJ X (NOD/LtJ x CAST/Ei)F1 or SKH2/J X (SKH2/J x CAST/Ei)F1	increased or absent threshold for auditory brainstem response	J:67312
	increased susceptibility to age-related hearing loss	J:67312
Cdh23^ahl/Cdh23^tm1.1Kjn Mahl^C57BL/6J/Mahl^129S1/SvImJ (129S1.B6-(rs3696307-rs257098870)/Kjn x 129S/Sv-Cdh23^tm1.1Kjn/Kjn)F1	increased or absent threshold for auditory brainstem response	J:241137
Cdh23^v-2J/Cdh23⁺ Pcdh15^av-3J/Pcdh15⁺ C57BL/6J-Cdh23^v-2J Pcdh15^av-3J	abnormal inner hair cell stereociliary bundle morphology	J:95655
	abnormal outer hair cell stereociliary bundle morphology	J:95655
	cochlear ganglion degeneration	J:95655
	cochlear hair cell degeneration	J:95655
	increased or absent threshold for auditory brainstem response	J:95655
	increased susceptibility to age-related hearing loss	J:95655
	normal vision/eye phenotype	J:95655
Cdh23^v-2J/Cdh23⁺ Espn^je/Espn⁺ (B6(V)-Cdh23^v-2J/J x JE/LeJ)F1	normal hearing/vestibular/ear phenotype	J:78812
Cdh23^v-2J/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	absent pinna reflex	J:108877
Cdh23^v-2J/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	increased susceptibility to age-related hearing loss	J:108877
Cdh23^v-2J/Cdh23⁺ Myo7a^sh1-8J/Myo7a⁺ B6.Cg-Myo7a^sh1-8J Cdh23^v-2J	increased or absent threshold for auditory brainstem response	J:183898
Cdh23^v/Cdh23⁺ Myo7a^sh1/Myo7a⁺ involves: BALB	deafness	J:13130
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ involves: BALB/cRl * 47BS/Rl * CBA/Ca	abnormal cochlear nerve compound action potential	J:134369
	abnormal outer hair cell stereociliary bundle morphology	J:134369
	decreased cochlear outer hair cell number	J:134369
	decreased outer hair cell stereocilia number	J:134369
	normal hearing/vestibular/ear phenotype	J:134369
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	absent pinna reflex	J:108877
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	increased susceptibility to age-related hearing loss	J:108877
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a^4626SB mixed	abnormal outer hair cell stereociliary bundle morphology	J:108877
Cdh23^v/Cdh23^v Myo7a^4626SB/Myo7a⁺ mixed	abnormal outer hair cell stereociliary bundle morphology	J:108877
Cdh23^v/Cdh23^v Myo7a^4626SB/Myo7a^4626SB involves: 47BS/Rl * CBA/Ca	abnormal eye electrophysiology	J:109546
	normal vision/eye phenotype	J:109546
Cdh23^v/Cdh23^v Myo7a^4626SB/Myo7a^4626SB mixed	abnormal outer hair cell stereociliary bundle morphology	J:108877
Fscn2^ahl8/Fscn2^ahl8 Cdh23^ahl/Cdh23^ahl involves: C57BL/6J * DBA/2J	increased or absent threshold for auditory brainstem response	J:139223
	increased susceptibility to age-related hearing loss	J:139223

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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