Laptm4b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Laptm4b
lysosomal-associated protein transmembrane 4B
MGI:1890494

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Laptm4b^em1Huty/Laptm4b^em1Huty C57BL/6-Laptm4b^em1Huty	abnormal lysosome morphology	J:310542
	normal cardiovascular system phenotype	J:310542
	normal growth/size/body region phenotype	J:310542
	impaired autophagy	J:310542
	increased myocardial infarct size	J:310542
	normal mortality/aging	J:310542
Laptm4b^{tm1e.1(KOMP)Wtsi}/Laptm4b⁺ C57BL/6N-Laptm4b^{tm1e.1(KOMP)Wtsi}/Tcp	decreased prepulse inhibition	J:211773
	increased startle reflex	J:211773
Laptm4b^{tm1e.1(KOMP)Wtsi}/Laptm4b^{tm1e.1(KOMP)Wtsi} C57BL/6N-Laptm4b^{tm1e.1(KOMP)Wtsi}/Tcp	abnormal craniofacial morphology	J:211773
	abnormal embryo size	J:211773
	abnormal eye morphology	J:211773
	abnormal hindbrain morphology	J:211773
	abnormal midbrain morphology	J:211773
	abnormal neural tube closure	J:211773
	edema	J:211773
	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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