Elac2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elac2
elaC ribonuclease Z 2
MGI:1890496

22 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elac2^em1Afi/Elac2^em1Afi C57BL/6N-Elac2^em1Afi	abnormal prostate gland anterior lobe morphology	J:336403
	abnormal prostate gland dorsolateral lobe morphology	J:336403
	normal mortality/aging	J:336403
	prostate gland anterior lobe hyperplasia	J:336403
	prostate gland dorsolateral lobe hyperplasia	J:336403
	prostate gland hyperplasia	J:336403
	prostate gland inflammation	J:336403
	normal reproductive system phenotype	J:336403
Elac2^{tm1b(EUCOMM)Wtsi}/Elac2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Elac2^{tm1b(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Elac2^{tm1c(EUCOMM)Wtsi}/Elac2^{tm1c(EUCOMM)Wtsi} Tg(Ckmm-cre)5Khn/0 involves: C57BL/6N * FVB	abnormal cell physiology	J:265839
	abnormal heart echocardiography feature	J:265839
	abnormal mitochondrial ATP synthesis coupled electron transport	J:265839
	abnormal mitochondrial physiology	J:265839
	abnormal oxidative phosphorylation	J:265839
	abnormal translation	J:265839
	normal cellular phenotype	J:265839
	decreased body weight	J:265839
	decreased cardiac muscle contractility	J:265839
	dilated cardiomyopathy	J:265839
	increased heart weight	J:265839
	premature death	J:265839
Elac2^{tm1d(EUCOMM)Wtsi}/Elac2^{tm1d(EUCOMM)Wtsi} involves: C57BL/6N	embryonic lethality, complete penetrance	J:265839

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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