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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Plin1
perilipin 1
MGI:1890505
42 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Plin1tm1Asg/Plin1tm1Asg
B6.129S6-Plin1tm1Asg 		abnormal brown adipose tissue morphology J:121641
abnormal brown adipose tissue physiology J:121641
abnormal circulating free fatty acids level J:113735
normal adipose tissue phenotype J:121641
decreased brown adipose tissue amount J:121641
decreased white adipose tissue mass J:121641
enhanced lipolysis J:113735
normal homeostasis/metabolism phenotype J:121641
Plin1tm1Asg/Plin1tm1Asg
Tg(Fabp4-Plin*)1Asg/0
involves: 129S6/SvEvTac * C57BL/6 		abnormal adipose tissue physiology J:113735
abnormal body temperature homeostasis J:121641
abnormal brown adipose tissue physiology J:121641
abnormal white adipose tissue mass J:121641
decreased brown adipose tissue amount J:121641
impaired lipolysis J:113735
Plin1tm1Cdl/Plin1tm1Cdl
involves: 129S6/SvEvTac * C57BL/6 		abnormal fat pad morphology J:69629
abnormal glucose homeostasis J:69629
abnormal lipolysis J:69629
abnormal liver morphology J:69629
decreased brown fat lipid droplet number J:69629
decreased epididymal fat pad weight J:69629
decreased inguinal fat pad weight J:69629
decreased parametrial fat pad weight J:69629
decreased retroperitoneal fat pad weight J:69629
decreased subcutaneous adipose tissue amount J:69629
decreased total body fat amount J:69629
decreased total fat pad weight J:69629
enhanced lipolysis J:69629
normal growth/size/body region phenotype J:69629
impaired glucose tolerance J:69629
impaired lipolysis J:69629
increased circulating insulin level J:69629
increased circulating leptin level J:69629
increased lean body mass J:69629
increased oxygen consumption J:69629
Plin1tm1Chan/Plin1tm1Chan
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal blood homeostasis J:66267
abnormal circulating free fatty acids level J:66267
abnormal circulating ketone body level J:66267
abnormal glycerol level J:66267
decreased brown fat cell lipid droplet size J:66267
decreased circulating leptin level J:66267
decreased epididymal fat pad weight J:66267
decreased interscapular fat pad weight J:66267
decreased subcutaneous adipose tissue amount J:66267
decreased susceptibility to diet-induced obesity J:66267
decreased total body fat amount J:66267
decreased total fat pad weight J:66267
decreased white fat cell size J:66267
enhanced lipolysis J:66267
impaired adaptive thermogenesis J:66267
increased food intake J:66267
increased gastrocnemius weight J:66267
increased lean body mass J:66267
increased oxygen consumption J:66267
Plin1tm2Lex/Plin1tm2Lex
involves: 129S5/SvEvBrd * C57BL/6J 		decreased percent body fat/body weight J:185494
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory