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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pramel1
PRAME like 1
MGI:1890541
27 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pramel1em1(IMPC)Tcp/Pramel1em1(IMPC)Tcp
C57BL/6NCrl-Pramel1em1(IMPC)Tcp/Tcp 		abnormal seminal vesicle morphology J:211773
abnormal skin morphology J:211773
decreased exploration in new environment J:211773
enlarged kidney J:211773
enlarged lymph nodes J:211773
enlarged urinary bladder J:211773
increased circulating alanine transaminase level J:211773
Pramel1em1Liuw/Pramel1em1Liuw
involves: C57BL/6 		abnormal male germ cell morphology J:342835
abnormal seminiferous tubule morphology J:342835
abnormal spermatogenesis J:342835
abnormal spermatogonia morphology J:342835
abnormal spermatogonia proliferation J:342835
abnormal testis physiology J:342835
decreased litter size J:342835
decreased male germ cell apoptosis J:342835
decreased male germ cell number J:342835
decreased spermatogonia number J:342835
enlarged seminiferous tubules J:342835
enlarged testis J:342835
increased litter size J:342835
increased male germ cell apoptosis J:342835
increased physiological sensitivity to xenobiotic J:342835
increased sperm number J:342835
oligozoospermia J:342835
small seminiferous tubules J:342835
small testis J:342835
Pramel1em1Liuw/Pramel1em1Liuw
Tg(Id4-EGFP)LT-11B6Oat/0
involves: C57BL/6 * FVB 		abnormal seminiferous tubule epithelium morphology J:342835
abnormal seminiferous tubule morphology J:342835
abnormal spermatogonia morphology J:342835
Pramel1em2Liuw/Pramel1em2Liuw
Tg(Stra8-icre)1Reb/0
involves: C57BL/6 * FVB/NJ 		abnormal seminiferous tubule morphology J:342835
decreased litter size J:342835
increased physiological sensitivity to xenobiotic J:342835
oligozoospermia J:342835
small testis J:342835
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory