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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Wasf1
WASP family, member 1
MGI:1890563
34 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Wasf1Gt(VICTR37)1Kwak/Wasf1Gt(VICTR37)1Kwak
involves: 129S5/SvEvBrd * C57BL/6 		abnormal brain development J:83377
abnormal cerebral cortex morphology J:83377
abnormal food intake J:83377
abnormal hepatocyte morphology J:83377
abnormal retrosplenial region morphology J:83377
abnormal small intestinal microvillus morphology J:83377
decreased body size J:83377
decreased brain size J:83377
decreased corpus callosum size J:83377
decreased striatum size J:83377
enlarged lateral ventricles J:83377
normal nervous system phenotype J:83377
postnatal growth retardation J:83377
premature death J:83377
skeletal muscle fiber atrophy J:83377
thin cerebral cortex J:83377
tremors J:83377
weakness J:83377
weight loss J:83377
Wasf1tm1Jsco/Wasf1tm1Jsco
involves: 129X1/SvJ * C57BL/6 		abnormal CNS synaptic transmission J:117303
abnormal excitatory postsynaptic potential J:117303
abnormal neuron morphology J:117303
abnormal neuron physiology J:117303
abnormal NMDA-mediated synaptic currents J:117303
abnormal object recognition memory J:81968
abnormal spatial learning J:81968
decreased anxiety-related response J:81968
decreased body weight J:81968
enhanced long-term potentiation J:117303
impaired balance J:81968
impaired coordination J:81968
postnatal lethality J:81968
reduced long-term depression J:117303
Wasf1tm2Jsco/Wasf1tm2Jsco
involves: 129X1/SvJ * C57BL/6 		abnormal excitatory postsynaptic potential J:117303
abnormal neuron morphology J:117303
abnormal response to novel object J:117303
abnormal spatial learning J:117303
enhanced long-term potentiation J:117303
normal nervous system phenotype J:117303
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory