Sptbn4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sptbn4
spectrin beta, non-erythrocytic 4
MGI:1890574

39 phenotypes from 15 alleles in 18 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sptbn4^{Gt(ROSABetageo)62Sor}/Sptbn4^{Gt(ROSABetageo)62Sor} 129S4/SvJaeSor-Spnb4^{Gt(ROSABetageo)62Sor}	abnormal muscle contractility	J:77228
	ataxia	J:77228
	limb grasping	J:77228
	tremors	J:77228
Sptbn4^{Gt(ROSABetageo)62Sor}/Sptbn4^{Gt(ROSABetageo)62Sor} B6.129S4-Sptbn4^{Gt(ROSABetageo)62Sor}/Mmucd	abnormal muscle contractility	J:77228
	ataxia	J:77228
	limb grasping	J:77228
	tremors	J:77228
Sptbn4^{Gt(ROSABetageo)62Sor}/Sptbn4^{Gt(ROSABetageo)62Sor} involves: 129S4/SvJaeSor * C57BL/6J	abnormal axon morphology	J:120916
	abnormal mating frequency	J:77228
	abnormal muscle contractility	J:77228, J:120916
	abnormal myelination	J:120916
	ataxia	J:77228
	limb grasping	J:77228
	tremors	J:77228
Sptbn4^qv-2J/Sptbn4^qv-2J CXB6/By Sptbn4^qv-2J	abnormal auditory brainstem response	J:14995
Sptbn4^qv-3J/Sptbn4^qv-3J C57BL/6J-Sptbn^qv-3J/J	abnormal auditory brainstem response	J:14995
	absent linear vestibular evoked potential	J:116914
	tremors	J:116914
Sptbn4^qv-4J/Sptbn4^qv-4J involves: C57BL/6J * CBA/CaJ * DBA/2J	abnormal auditory brainstem response waveform shape	J:71549
	increased or absent threshold for auditory brainstem response	J:71549
Sptbn4^qv-7J/Sptbn4^qv-7J A.B6 Tyr⁺-Sptbn4^qv-7J/J	normal muscle phenotype	J:82238
Sptbn4^qv-7J/Sptbn4^qv-7J A.B6 Tyr⁺-Sptbn4^qv-7J/J	paraparesis	J:82238
Sptbn4^qv-8J/Sptbn4^qv-8J C57BL/6J-Sptbn4^qv-8J/J	tremors	J:82238
Sptbn4^qv-9J/Sptbn4^qv-9J involves: BALB/cByJ * C57BL/6J	abnormal posture	J:87349
	head bobbing	J:87349
	increased vertical activity	J:87349
	limb grasping	J:87349
	tremors	J:87349
Sptbn4^qv-10J/Sptbn4^qv-10J involves: BALB/cJ * C57BL/6J	abnormal gait	J:137504
	ataxia	J:137504
	deafness	J:137504
	impaired balance	J:137504
	increased or absent threshold for auditory brainstem response	J:137504
	male infertility	J:137504
	normal mortality/aging	J:137504
	tremors	J:137504
	normal vision/eye phenotype	J:137504
Sptbn4^qv-11J/Sptbn4^qv-11J C57BL/6J-Sptbn4^qv-11J/J	abnormal gait	J:137504
	impaired hearing	J:137504
	increased or absent threshold for auditory brainstem response	J:137504
	male infertility	J:137504
	normal mortality/aging	J:137504
	tremors	J:137504
Sptbn4^qv-J/Sptbn4^qv-J C3FeB6 A/A^w-J-Sptbn4^qv-J/J	normal muscle phenotype	J:37678
Sptbn4^qv-J/Sptbn4^qv-J C3FeB6 A/A^w-J-Sptbn4^qv-J/J	tremors	J:20207
Sptbn4^qv-lnd2J/Sptbn4⁺ C3H/HeJ-Sptbn4^qv-lnd2J/J	reduced linear vestibular evoked potential	J:116914
Sptbn4^qv-lnd2J/Sptbn4^qv-lnd2J C3H/HeJ-Sptbn4^qv-lnd2J/J	abnormal auditory brainstem response waveform shape	J:71549
	abnormal auditory cortex morphology	J:71549
	absent linear vestibular evoked potential	J:116914
	increased or absent threshold for auditory brainstem response	J:71549
	premature death	J:30329
Sptbn4^qv-lnd/Sptbn4^qv-lnd B6.B10-Sptbn4^qv-lnd	abnormal gait	J:11718
	axonal dystrophy	J:11718
	decreased body size	J:11718
	male infertility	J:11718
	paresis	J:11718
	tremors	J:11718
Sptbn4^qv/Sptbn4^qv either: (involves: BALB/c) or (involves: C57BL/10)	ataxia	J:167
	deafness	J:167
	eye inflammation	J:167
	hindlimb paralysis	J:167
	male infertility	J:167
	paralysis	J:167
	premature death	J:167
	priapism	J:167
	tremors	J:167
Sptbn4^qv/Sptbn4^qv involves: CBA/Gr	abnormal auditory brainstem response	J:71549
Sptbn4^qv/Sptbn4^qv Not Specified	deafness	J:32693
Sptbn4^tm1Mkom/Sptbn4^tm1Mkom involves: 129S4/SvJaeSor * C57BL/6J	abnormal axon morphology	J:120916
	abnormal myelination	J:120916
	normal reproductive system phenotype	J:120916
	tremors	J:120916
Sptbn4^tm1Msol/Sptbn4^tm1Msol involves: C57BL/6	abnormal auditory brainstem response	J:93411
	abnormal cerebellum morphology	J:93411
	abnormal gait	J:93411
	abnormal optic nerve morphology	J:93411
	abnormal sciatic nerve morphology	J:93411
	decreased body weight	J:93411
	dysmetria	J:93411
	tremors	J:93411

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