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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Brwd1
bromodomain and WD repeat domain containing 1
MGI:1890651
24 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Brwd1em1(IMPC)Tcp/Brwd1em1(IMPC)Tcp
C57BL/6N-Brwd1em1(IMPC)Tcp/Cmmr 		abnormal seminal vesicle morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
female infertility J:211773
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
male infertility J:211773
small testis J:211773
Brwd1Gt(AW0417)Wtsi/Brwd1Gt(AW0417)Wtsi
involves: 129P2/OlaHsd 		abnormal female meiosis J:136078
abnormal male germ cell morphology J:136078
decreased male germ cell number J:136078
Brwd1Gt(AW0417)Wtsi/Brwd1repro5
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		asthenozoospermia J:136078
decreased male germ cell number J:136078
globozoospermia J:136078
Brwd1repro5/Brwd1repro5
involves: C3HeB/FeJ * C57BL/6J 		abnormal female meiosis J:136078
abnormal male germ cell morphology J:136078
abnormal oocyte morphology J:92463
abnormal reproductive system morphology J:136078
abnormal reproductive system physiology J:136078
abnormal sperm flagellum morphology J:136078
abnormal sperm head morphology J:136078
abnormal sperm midpiece morphology J:136078
abnormal spermiogenesis J:92463
asthenozoospermia J:92463, J:136078
female infertility J:92463, J:136078
globozoospermia J:92463, J:136078
impaired fertilization J:136078
male infertility J:92463, J:136078
necrospermia J:136078
oligozoospermia J:92463
teratozoospermia J:136078
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory