Kcne3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcne3
potassium voltage-gated channel, Isk-related subfamily, gene 3
MGI:1891124

19 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcne3^{tm1(KOMP)Vlcg}/Kcne3^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal action potential	J:215948
	abnormal hearing electrophysiology	J:215948
Kcne3^{tm1.1(KOMP)Vlcg}/Kcne3^{tm1.1(KOMP)Vlcg} C57BL/6NCrl-Kcne3^{tm1.1(KOMP)Vlcg}/MbpMmucd	abnormal eye morphology	J:211773
	decreased circulating total protein level	J:211773
Kcne3^tm1.1Tjj/Kcne3^tm1.1Tjj involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	abnormal digestive system physiology	J:160721
	abnormal intestine physiology	J:160721
	abnormal physiological response to xenobiotic	J:160721
	abnormal respiratory system physiology	J:160721
Kcne3^tm1Gwab/Kcne3^tm1Gwab B6.Cg-Kcne3^tm1Gwab Tyr^c-2J	normal digestive/alimentary phenotype	J:170745
Kcne3^tm1Gwab/Kcne3^tm1Gwab involves: C57BL/6	abnormal adrenal gland morphology	J:210381
	abnormal cardiovascular system physiology	J:210381
	abnormal T wave	J:210381
	decreased circulating HDL cholesterol level	J:210381
	increased circulating aldosterone level	J:210381
	increased circulating cholesterol level	J:210381
	increased circulating LDL cholesterol level	J:210381
	increased inflammatory response	J:210381
	prolonged QT interval	J:210381
	ventricular tachycardia	J:210381

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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