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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ube3b
ubiquitin protein ligase E3B
MGI:1891295
42 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ube3bem1(IMPC)Bay/Ube3b+
C57BL/6N-Ube3bem1(IMPC)Bay/Bay 		abnormal cornea morphology J:211773
abnormal eye anterior chamber depth J:211773
abnormal iris morphology J:211773
abnormal lens morphology J:211773
abnormal retina inner nuclear layer morphology J:211773
abnormal retina vasculature morphology J:211773
eye hemorrhage J:211773
fused cornea and lens J:211773
increased cornea thickness J:211773
iris synechia J:211773
Ube3bem1(IMPC)Bay/Ube3bem1(IMPC)Bay
C57BL/6N-Ube3bem1(IMPC)Bay/Bay 		abnormal embryo size J:211773
abnormal facial morphology J:211773
preweaning lethality, complete penetrance J:211773
Ube3bGt(RRJ142)Byg/Ube3bGt(RRJ142)Byg
involves: 129P2/OlaHsd * CBA/Ca 		calcified retina J:203652
decreased body size J:203652
decreased body weight J:203652
decreased brain size J:203652
decreased circulating cholesterol level J:203652
decreased circulating LDL cholesterol level J:203652
decreased dentate gyrus size J:203652
decreased grip strength J:203652
eye inflammation J:203652
normal hearing/vestibular/ear phenotype J:203652
impaired hearing J:203652
lymphangiectasis J:203652
normal nervous system phenotype J:203652
preweaning lethality, incomplete penetrance J:203652
reduced fertility J:203652
small hippocampus J:203652
Ube3btm1a(EUCOMM)Hmgu/Ube3btm1a(EUCOMM)Hmgu
C57BL/6-Ube3btm1a(EUCOMM)Hmgu 		abnormal behavior J:273879
abnormal corpus callosum morphology J:273879
abnormal dendrite morphology J:273879
abnormal mitochondrial physiology J:273879
abnormal nest building behavior J:273879
abnormal primary somatosensory cortex morphology J:273879
abnormal synapse morphology J:273879
decreased body length J:273879
decreased body weight J:273879
decreased dendritic spine density J:273879
decreased grip strength J:273879
decreased vocalization J:273879
enlarged brain ventricles J:273879
poor grooming J:273879
postnatal growth retardation J:273879
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory