Prg4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prg4
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
MGI:1891344

18 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prg4^{em1(IMPC)Ccpcz}/Prg4^{em1(IMPC)Ccpcz} C57BL/6N-Prg4^{em1(IMPC)Ccpcz}/Ccpcz	abnormal joint morphology	J:211773
	abnormal skin morphology	J:211773
	decreased body weight	J:211773
	decreased exploration in new environment	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	improved glucose tolerance	J:211773
	increased anxiety-related response	J:211773
	increased circulating potassium level	J:211773
Prg4^{tm1(GFP/cre/ERT2)Abl}/Prg4^{tm1(GFP/cre/ERT2)Abl} involves: 129 * C57BL/6J	abnormal joint morphology	J:197163
	decreased chondrocyte number	J:197163
	normal mortality/aging	J:197163
Prg4^tm1Mawa/Prg4^tm1Mawa involves: 129S1/Sv * 129X1/SvJ	abnormal articular cartilage morphology	J:96756
	abnormal gait	J:96756
	abnormal joint morphology	J:96756
	abnormal long bone epiphyseal plate morphology	J:96756
	calcified joint	J:96756
	camptodactyly	J:96756
	normal cardiovascular system phenotype	J:96756
	joint swelling	J:96756

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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