Brdt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Brdt
bromodomain, testis-specific
MGI:1891374

22 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brdt^{tm1a(EUCOMM)Wtsi}/Brdt^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Brdt^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased lumbar vertebrae number	J:165965
	increased sacral vertebrae number	J:165965
Brdt^{tm1a(EUCOMM)Wtsi}/Brdt^{tm1a(EUCOMM)Wtsi} C57BL/6-Brdt^{tm1a(EUCOMM)Wtsi}	abnormal male accessory sex gland morphology	J:232496
	abnormal seminiferous tubule morphology	J:232496
	abnormal spermatid morphology	J:232496
	abnormal spermatocyte morphology	J:232496
	abnormal spermatogenesis	J:232496
	arrest of male meiosis	J:232496
	azoospermia	J:232496
	decreased circulating testosterone level	J:232496
	decreased testis weight	J:232496
	delayed sexual maturation	J:232496
	increased male germ cell apoptosis	J:232496
	male infertility	J:232496
Brdt^{tm1a(EUCOMM)Wtsi}/Brdt^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	arrest of male meiosis	J:190041
Brdt^tm1Djw/Brdt^tm1Djw involves: 129S/SvEv * C57BL/6J	abnormal acrosome assembly	J:128000
	abnormal sperm flagellum morphology	J:128000
	abnormal sperm head morphology	J:128000
	abnormal sperm midpiece morphology	J:128000
	abnormal spermatid morphology	J:128000
	asthenozoospermia	J:128000
	male infertility	J:128000
	oligozoospermia	J:128000
	normal reproductive system phenotype	J:128000
	teratozoospermia	J:128000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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