Brdt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Brdt
bromodomain, testis-specific
MGI:1891374

22 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brdt^{tm1a(EUCOMM)Wtsi}/Brdt^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Brdt^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased lumbar vertebrae number	J:165965
	increased sacral vertebrae number	J:165965
Brdt^{tm1a(EUCOMM)Wtsi}/Brdt^{tm1a(EUCOMM)Wtsi} C57BL/6-Brdt^{tm1a(EUCOMM)Wtsi}	abnormal male accessory sex gland morphology	J:232496
	abnormal seminiferous tubule morphology	J:232496
	abnormal spermatid morphology	J:232496
	abnormal spermatocyte morphology	J:232496
	abnormal spermatogenesis	J:232496
	arrest of male meiosis	J:232496
	azoospermia	J:232496
	decreased circulating testosterone level	J:232496
	decreased testis weight	J:232496
	delayed sexual maturation	J:232496
	increased male germ cell apoptosis	J:232496
	male infertility	J:232496
Brdt^{tm1a(EUCOMM)Wtsi}/Brdt^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	arrest of male meiosis	J:190041
Brdt^tm1Djw/Brdt^tm1Djw involves: 129S/SvEv * C57BL/6J	abnormal acrosome assembly	J:128000
	abnormal sperm flagellum morphology	J:128000
	abnormal sperm head morphology	J:128000
	abnormal sperm midpiece morphology	J:128000
	abnormal spermatid morphology	J:128000
	asthenozoospermia	J:128000
	male infertility	J:128000
	oligozoospermia	J:128000
	normal reproductive system phenotype	J:128000
	teratozoospermia	J:128000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24