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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ncstn
nicastrin
MGI:1891700
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Gt(ROSA)26Sortm1.1(rtTA2S*M2)Whsu/Gt(ROSA)26Sor+
Ncstntm1.1Akli/Ncstntm1.1Akli
Tg(tetO-cre)1Jaw/0
involves: 129 * 129S6/SvEvTac * C57BL/6
hydronephrosis J:227748
increased urinary bladder carcinoma incidence J:227748
ureter obstruction J:227748
Ncstntm1.1Akli/Ncstntm1.1Akli
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tg(VAV1-cre)1Graf/0
involves: 129S/SvEv * C57BL/6
abnormal common myeloid progenitor cell morphology J:196407
abnormal tumor pathology J:196407
enlarged spleen J:196407
increased leukemia incidence J:196407
increased leukocyte cell number J:196407
myeloid hyperplasia J:196407
premature death J:196407

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory