Hbs1l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hbs1l
Hbs1-like (S. cerevisiae)
MGI:1891704

56 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hbs1l^Gt(XE494)Byg/Hbs1l^Gt(XE494)Byg involves: 129P2/OlaHsd	embryonic lethality between implantation and somite formation, complete penetrance	J:306384
Hbs1l^{tm1a(KOMP)Wtsi}/Hbs1l^{tm1a(KOMP)Wtsi} C57BL/6N-Hbs1l^{tm1a(KOMP)Wtsi}/Wtsi	abnormal bone structure	J:211773
	abnormal cranium morphology	J:211773
	abnormal facial morphology	J:272028
	abnormal nasal bone morphology	J:272028
	abnormal retina morphology	J:211773
	abnormal retina pigmentation	J:272028
	abnormal snout morphology	J:211773
	abnormal tail morphology	J:211773
	abnormal tooth morphology	J:272028
	abnormal vertebrae morphology	J:272028
	abnormal zygomatic bone morphology	J:272028
	asymmetric snout	J:272028
	cornea opacity	J:211773
	decreased body weight	J:272028
	decreased bone mineral content	J:211773
	decreased effector memory CD8-positive, alpha-beta T cell number	J:211773
	decreased Langerhans cell number	J:211773
	decreased mature B cell number	J:211773
	decreased memory-marker CD4-negative NK T cell number	J:211773
	decreased monocyte cell number	J:211773
	decreased T-helper cell number	J:211773
	decreased total body fat amount	J:211773
	improved glucose tolerance	J:211773
	increased CD4-positive, alpha-beta memory T cell number	J:211773
	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
	increased CD5-positive gamma-delta T cell number	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating free fatty acids level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating iron level	J:211773
	increased circulating total protein level	J:211773
	increased effector memory CD8-positive, alpha-beta T cell number	J:211773
	increased leukocyte cell number	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean platelet volume	J:211773
	increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
	increased regulatory T cell number	J:211773
	male infertility	J:211773, J:272028
	malocclusion	J:272028
	short nasal bone	J:272028
	short snout	J:272028
	thrombocytosis	J:211773
	vertebral transformation	J:211773, J:272028
Hbs1l^{tm1a(KOMP)Wtsi}/Hbs1l^{tm1a(KOMP)Wtsi} C57BL/6NTac-Hbs1l^{tm1a(KOMP)Wtsi}	oligozoospermia	J:306384
Hbs1l^{tm1c(KOMP)Wtsi}/Hbs1l^{tm1c(KOMP)Wtsi} En1^tm2(cre)Wrst/En1⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6NTac	abnormal cerebellar foliation	J:306384
	abnormal cerebellum morphology	J:306384
	abnormal GABAergic neuron morphology	J:306384
	decreased neuronal precursor cell number	J:306384
	decreased Purkinje cell number	J:306384
	increased neuronal precursor proliferation	J:306384
	small cerebellum	J:306384
Hbs1l^{tm1c(KOMP)Wtsi}/Hbs1l^{tm1c(KOMP)Wtsi} Tg(Atoh1-cre)1Bfri/0 involves: 129S4/SvJaeSor * C57BL/6NTac * CBA	normal nervous system phenotype	J:306384
Hbs1l^{tm1c(KOMP)Wtsi}/Hbs1l^{tm1c(KOMP)Wtsi} Tg(Gabra6-cre)B1Lfr/0 involves: 129S4/SvJaeSor * C57BL/6NTac * DBA/2	normal nervous system phenotype	J:306384
Hbs1l^{tm1d(KOMP)Wtsi}/Hbs1l^{tm1d(KOMP)Wtsi} B6(Cg)-Hbs1l^{tm1d(KOMP)Wtsi}	embryonic growth arrest	J:306384
	embryonic lethality during organogenesis, complete penetrance	J:306384

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