Stub1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stub1
STIP1 homology and U-Box containing protein 1
MGI:1891731

33 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stub1^em1Schiz/Stub1^em1Schiz C57BL/6J-Stub1^em1Schiz	decreased fluid intake	J:260672
	increased urine chloride ion level	J:260672
	increased urine creatinine level	J:260672
	increased urine osmolality	J:260672
	increased urine potassium level	J:260672
	increased urine sodium level	J:260672
	increased urine urea nitrogen level	J:260672
Stub1^tm1Atak/Stub1^tm1Atak B6.Cg-Stub1^tm1Atak	ataxia	J:100900
	decreased body weight	J:100900
	postnatal lethality, incomplete penetrance	J:100900
	tau protein deposits	J:100900
Stub1^tm1Cpat/Stub1^tm1Cpat involves: 129S/SvEv	abnormal cerebellum morphology	J:206229
	abnormal Purkinje cell dendrite morphology	J:206229
	abnormal response to new environment	J:206229
	ataxia	J:206229
	decreased follicle stimulating hormone level	J:206229
	decreased startle reflex	J:206229
	decreased testis weight	J:206229
	impaired coordination	J:206229
	impaired spatial learning	J:206229
	Purkinje cell degeneration	J:206229
	reduced fertility	J:206229
	short stride length	J:206229
Stub1^tm1Cpat/Stub1^tm1Cpat involves: 129S/SvEv * C57BL/6	abnormal apoptosis	J:86213
	abnormal cell physiology	J:86213
	abnormal muscle fiber morphology	J:245069
	abnormal sarcoplasmic reticulum morphology	J:245069
	abnormal skeletal muscle fiber type ratio	J:245069
	decreased fluid intake	J:260672
	increased susceptibility to injury	J:86213
	increased thymocyte apoptosis	J:86213
	increased urine chloride ion level	J:260672
	increased urine creatinine level	J:260672
	increased urine osmolality	J:260672
	increased urine potassium level	J:260672
	increased urine sodium level	J:260672
	increased urine urea nitrogen level	J:260672
	perinatal lethality, incomplete penetrance	J:86213
	postnatal lethality, incomplete penetrance	J:86213
	thymus atrophy	J:86213
	thymus hypoplasia	J:86213
Stub1^tm1Lex/Stub1^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased body weight	J:103485
	premature death	J:103485

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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