About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dact1
dishevelled-binding antagonist of beta-catenin 1
MGI:1891740
59 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Dact1tm1.1Bnrc/Dact1tm1.1Bnrc
B6.Cg-Dact1tm1.1Bnrc 		abnormal blood circulation J:152701
abnormal colon morphology J:152701
abnormal ectoderm development J:152701
abnormal embryonic tissue morphology J:152701
abnormal endoderm development J:152701
abnormal paraxial mesoderm morphology J:152701
abnormal posterior definitive endoderm morphology J:152701
abnormal presomitic mesoderm morphology J:152701
abnormal primitive streak morphology J:152701
abnormal somite development J:152701
abnormal tail bud morphology J:152701
abnormal tailgut morphology J:152701
abnormal ureter morphology J:152701
abnormal vertebrae morphology J:152701
absent anus J:152701
absent external female genitalia J:152701
absent external male genitalia J:152701
absent kidney J:152701
absent urinary bladder J:152701
caudal body truncation J:152701
decreased caudal vertebrae number J:152701
decreased survivor rate J:152701
fused kidneys J:152701
hydrometrocolpos J:152701
hydronephrosis J:152701
impaired somite development J:152701
megacolon J:152701
neonatal lethality, incomplete penetrance J:152701
short tail J:152701
sirenomelia J:152701
small notochord J:152701
spina bifida J:152701
urethra atresia J:152701
Dact1tm1.1Bnrc/Dact1tm1.1Bnrc
involves: 129 		abnormal dendritic spine morphology J:159217
abnormal genital tubercle morphology J:201925
abnormal synapse morphology J:159217
decreased miniature excitatory postsynaptic current frequency J:159217
short tail J:201925
Dact1tm1.1Bnrc/Dact1tm1.2Bnrc
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas 		abnormal dendritic spine morphology J:159217
normal nervous system phenotype J:159217
Dact1tm1Yegc/Dact1tm1Yegc
B6.129-Dact1tm1Yegc 		abnormal embryonic cloaca morphology J:161177
abnormal hindgut morphology J:161177
abnormal ilium morphology J:161177
abnormal kidney morphology J:161177
abnormal lumbar vertebrae morphology J:161177
abnormal notochord morphology J:161177
abnormal presomitic mesoderm morphology J:161177
abnormal primitive urogenital sinus morphology J:161177
abnormal renal/urinary system morphology J:161177
abnormal sacral vertebrae morphology J:161177
abnormal vas deferens morphology J:161177
abnormal vertebrae morphology J:161177
absent anus J:161177
absent external female genitalia J:161177
absent external male genitalia J:161177
absent kidney J:161177
absent urinary bladder J:161177
absent vagina J:161177
blind ureter J:161177
blind uterus J:161177
decreased birth body size J:161177
decreased caudal vertebrae number J:161177
decreased survivor rate J:161177
female infertility J:161177
fused kidneys J:161177
hydrometra J:161177
hydronephrosis J:161177
kidney cyst J:161177
neonatal lethality, incomplete penetrance J:161177
short tail J:161177
short ureter J:161177
single kidney J:161177
truncated notochord J:161177
ureter hypoplasia J:161177
urethra atresia J:161177
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory