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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Becn1
beclin 1, autophagy related
MGI:1891828
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Becn1tm1Blev/Becn1+
Tg(Alb1HBV)44Bri/0
involves: 129X1/SvJ * C57BL/6J 		increased tumor incidence J:86953
Becn1tm1Blev/Becn1+
Tg(CAG-EGFP/Map1lc3b)53Nmz/0
involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrj 		impaired autophagy J:86953
Becn1tm1Blev/Becn1+
Tg(CAG-EGFP/Map1lc3b)53Nmz/0
involves: 129X1/SvJ * C57BL/6NCrj 		impaired autophagy J:181308
impaired exercise endurance J:181308
Becn1tm1Smoc/Becn1tm1Smoc
Zfp91tm1Smoc/Zfp91tm1Smoc
Foxp3tm4(YFP/icre)Ayr/Y
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal regulatory T cell physiology J:306129
Becn1tm2.1Blev/Becn1tm2.1Blev
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
involves: 129 * C57BL/6 * C57BL/6J * SJL 		amyloid beta deposits J:244104
normal behavior/neurological phenotype J:244104
Becn1tm2.1Blev/Becn1tm2.1Blev
Tg(APPV717F)109Ili/0
B6.Cg-Becn1tm2.1Blev Tg(APPV717F)109Ili 		extended life span J:244104
Becn1tm2.1Blev/Becn1tm2.1Blev
Tg(CAG-EGFP/Map1lc3b)53Nmz/0
involves: 129 * C57BL/6 * C57BL/6J * C57BL/6NCrlj * DBA/2 		enhanced autophagy J:244104
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory