Pkp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pkp3
plakophilin 3
MGI:1891830

31 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pkp3^tm1.1Fvr/Pkp3⁺ involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL	abnormal coat appearance	J:136451
	retarded hair growth	J:136451
Pkp3^tm1.1Fvr/Pkp3^tm1.1Fvr involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL	abnormal auchene hair morphology	J:136451
	abnormal awl hair morphology	J:136451
	abnormal coat appearance	J:136451
	abnormal epidermal layer morphology	J:136451
	abnormal hair cuticle	J:136451
	abnormal hair follicle inner root sheath morphology	J:136451
	abnormal hair follicle orientation	J:136451
	abnormal hair medulla	J:136451
	abnormal hair medulla air spaces	J:136451
	abnormal vibrissa follicle morphology	J:136451
	abnormal zigzag hair morphology	J:136451
	acanthosis	J:136451
	alopecia	J:136451
	brittle hair	J:136451
	cachexia	J:136451
	dermatitis	J:136451
	disheveled coat	J:136451
	enlarged lymph nodes	J:136451
	epidermal hyperplasia	J:136451
	increased hair follicle apoptosis	J:136451
	increased keratinocyte apoptosis	J:136451
	increased keratinocyte proliferation	J:136451
	matted coat	J:136451
	parakeratosis	J:136451
	reddish skin	J:136451
	retarded hair growth	J:136451
	ruffled hair	J:136451
	sparse hair	J:136451
	thick epidermis	J:136451
	underdeveloped hair follicles	J:136451
Pkp3^tm1Fvr/Pkp3^tm1Fvr involves: 129P2/OlaHsd * C57BL/6 * SJL	no abnormal phenotype detected	J:136451

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24