Patz1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Patz1
POZ (BTB) and AT hook containing zinc finger 1
MGI:1891832

43 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Patz1^{tm1.1(KOMP)Vlcg}/Patz1^{tm1.1(KOMP)Vlcg} C57BL/6N-Patz1^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
Patz1^tm1.1Welm/Patz1^tm1.1Welm involves: 129P2/OlaHsd	abnormal T cell subpopulation ratio	J:158947
	decreased body size	J:158947
	decreased body weight	J:158947
	decreased splenocyte number	J:158947
	decreased thymocyte number	J:158947
	prenatal lethality, incomplete penetrance	J:158947
Patz1^tm1.1Welm/Patz1^tm1.1Welm involves: 129P2/OlaHsd * C57BL/6	prenatal lethality	J:158947
Patz1^tm1.2Welm/Patz1^tm1.2Welm involves: 129P2/OlaHsd	no abnormal phenotype detected	J:209168
Patz1^tm1.2Welm/Patz1^tm1.2Welm Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ B6.Cg-Patz1^tm1.2Welm Commd10^{Tg(Vav1-icre)A2Kio}	abnormal mast cell differentiation	J:209168
	decreased interleukin-6 secretion	J:209168
	normal immune system phenotype	J:209168
Patz1^tm1.2Welm/Patz1^tm1.2Welm Tg(Cma1-cre)#Roer/0 involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:209168
Patz1^tm1Pchi/Patz1⁺ involves: C57BL/6J	increased fibroblast proliferation	J:190572
Patz1^tm1Pchi/Patz1^tm1Pchi involves: C57BL/6J	abnormal brain morphology	J:190572
	abnormal cardiac outflow tract development	J:190572
	abnormal cell cycle	J:190572
	abnormal choroid plexus morphology	J:190572
	abnormal descending aorta morphology	J:190572
	abnormal diencephalon morphology	J:190572
	abnormal embryonic neuroepithelium morphology	J:190572
	abnormal embryonic/fetal subventricular zone morphology	J:190572
	abnormal hindbrain morphology	J:190572
	decreased body size	J:190572
	decreased body weight	J:190572
	decreased brain size	J:190572
	decreased fetal size	J:190572
	decreased fibroblast proliferation	J:190572
	early cellular replicative senescence	J:190572
	embryonic lethality during organogenesis, incomplete penetrance	J:190572
	enlarged brain ventricles	J:190572
	exencephaly	J:190572
	incomplete rostral neuropore closure	J:190572
	lethality throughout fetal growth and development, incomplete penetrance	J:190572
	postnatal growth retardation	J:190572
	transposition of great arteries	J:190572
Patz1^tm1Pchi/Patz1^tm1Pchi Not Specified	abnormal seminiferous tubule morphology	J:133515
	abnormal spermatogonia proliferation	J:133515
	arrest of spermatogenesis	J:133515
	azoospermia	J:133515
	decreased testis weight	J:133515
	female infertility	J:133515
	increased Leydig cell number	J:133515
	male infertility	J:133515
	small seminiferous tubules	J:133515
	small testis	J:133515

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24