Hdac7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hdac7
histone deacetylase 7
MGI:1891835

18 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hdac7^{tm1b(EUCOMM)Hmgu}/Hdac7⁺ C57BL/6N-Hdac7^{tm1b(EUCOMM)Hmgu}/Kmpc	abnormal coat/hair pigmentation	J:211773
	increased circulating alkaline phosphatase level	J:211773
Hdac7^{tm1b(EUCOMM)Hmgu}/Hdac7^{tm1b(EUCOMM)Hmgu} C57BL/6N-Hdac7^{tm1b(EUCOMM)Hmgu}/Kmpc	embryonic lethality prior to tooth bud stage	J:211773
Hdac7^tm1Eno/Hdac7^tm1Eno either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)	abnormal cardinal vein morphology	J:116008
	abnormal dorsal aorta morphology	J:116008
	abnormal pharyngeal arch artery morphology	J:116008
	abnormal vascular endothelial cell morphology	J:116008
	abnormal vasculogenesis	J:116008
	dilated heart atrium	J:116008
	embryonic lethality during organogenesis, complete penetrance	J:116008
	internal hemorrhage	J:116008
	pericardial effusion	J:116008
	thin ventricular wall	J:116008
Hdac7^tm1Eno/Hdac7^tm2Eno Tg(Tek-cre)1Ywa/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal cardiovascular system morphology	J:116008
	abnormal vascular endothelial cell morphology	J:116008
	abnormal vascular smooth muscle morphology	J:116008
	dilated dorsal aorta	J:116008
	edema	J:116008
	embryonic lethality, complete penetrance	J:116008
	internal hemorrhage	J:116008

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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