Mkks Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mkks
McKusick-Kaufman syndrome
MGI:1891836

26 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mkks^{Gt(OST367255)Lex}/Mkks^{Gt(OST367255)Lex} involves: 129S5/SvEvBrd * C57BL/6J	abnormal inner hair cell kinocilium location or orientation	J:102697
	abnormal olfactory epithelium morphology	J:102697
	abnormal orientation of outer hair cell stereociliary bundles	J:102697
	absent distortion product otoacoustic emissions	J:102697
	absent pinna reflex	J:102697
	anosmia	J:102697
	exencephaly	J:102697
	eyelids open at birth	J:102697
	increased susceptibility to age-related retinal degeneration	J:102697
Mkks^tm1Vcs/Mkks^tm1Vcs either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal olfaction	J:99276
	absent sperm flagellum	J:99276
	decreased aggression	J:99276
	decreased body weight	J:99276
	decreased locomotor activity	J:99276
	decreased vocalization	J:99276
	increased circulating leptin level	J:99276
	increased susceptibility to age-related retinal degeneration	J:99276
	increased systemic arterial blood pressure	J:99276
	normal limbs/digits/tail phenotype	J:99276
	male infertility	J:99276
	obese	J:99276
	prenatal lethality, incomplete penetrance	J:99276
Mkks^tm1Vcs/Mkks^tm1Vcs involves: 129S1/Sv * 129X1/SvJ	decreased striatum size	J:128532
	enlarged lateral ventricles	J:128532
	enlarged third ventricle	J:128532
	small hippocampus	J:128532
	thin cerebral cortex	J:128532

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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