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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sh3rf1
SH3 domain containing ring finger 1
MGI:1913066
16 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sh3rf1em1(IMPC)J/Sh3rf1em1(IMPC)J
C57BL/6NJ-Sh3rf1em1(IMPC)J/Mmjax 		abnormal optic disk morphology J:211773
decreased exploration in new environment J:211773
Sh3rf1em1Bcgen/Sh3rf1em1Bcgen
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL 		abnormal nest building behavior J:326378
abnormal spatial reference memory J:326378
decreased body weight J:326378
decreased excitatory postsynaptic current amplitude J:326378
decreased social investigation J:326378
decreased vocalization J:326378
hypoactivity J:326378
impaired contextual conditioning behavior J:326378
impaired spatial learning J:326378
increased stereotypic behavior J:326378
reduced long-term potentiation J:326378
normal taste/olfaction phenotype J:326378
Sh3rf1em1Bcgen/Sh3rf1em1Bcgen
Tg(Nes-cre)1Kln/0
Tg(Thy1-EGFP)MJrs/0
involves: C57BL/6 * CBA * SJL 		decreased dendritic spine density J:326378
decreased dendritic spine length J:326378
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory