Sostdc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sostdc1
sclerostin domain containing 1
MGI:1913292

33 phenotypes from 8 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sostdc1^shk/Sostdc1^shk B6.Cg-Sostdc1^shk H2^g7/GrsrJ	abnormal hard palate morphology	J:127012
	abnormal palatal rugae morphology	J:154916
	abnormal palate morphology	J:127012
	decreased cranium height	J:127012
	decreased cranium width	J:127012
	short mandible	J:127012
	supernumerary incisors	J:127012
Sostdc1^shk/Sostdc1^shk involves: C57BL/6J * CAST/EiJ * NOD	supernumerary incisors	J:127012
Sostdc1^{tm1.1(KOMP)Vlcg}/Sostdc1^{tm1.1(KOMP)Vlcg} C57BL/6N-Sostdc1^{tm1.1(KOMP)Vlcg}/Ucd	persistence of hyaloid vascular system	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Sostdc1^tm1Myan/Sostdc1^tm1Myan involves: 129X1/SvJ * C57BL/6J	decreased physiological sensitivity to xenobiotic	J:105264
	decreased renal tubule apoptosis	J:105264
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:105264
	fused molars	J:105264
	supernumerary teeth	J:105264
Sostdc1^tm1Nit/Sostdc1^tm1Nit involves: 129S1/Sv * C57BL/6	abnormal enamel knot morphology	J:101382
	abnormal molar crown morphology	J:101382
	abnormal molar cusp morphology	J:101382
	fused molars	J:101382
	supernumerary molars	J:101382
Sostdc1^tm1Noit/Sostdc1^tm1Noit involves: C57BL/6 * CBA	abnormal trigeminal ganglion morphology	J:137689
Sostdc1^tm1Noit/Sostdc1^tm1Noit involves: C57BL/6 * CBA	neonatal lethality, incomplete penetrance	J:137689
Sostdc1^tm1Snd/Sostdc1^tm1Snd involves: C57BL/6	abnormal bone mineralization	J:216098
	abnormal bone ossification	J:216098
	abnormal osteoblast physiology	J:216098
	decreased chondrocyte proliferation	J:216098
	decreased osteoclast cell number	J:216098
	increased bone mass	J:216098
	increased bone mineral content	J:216098
	increased bone mineral density	J:216098
	increased osteoblast cell number	J:216098
	increased osteoblast proliferation	J:216098
	increased trabecular bone volume	J:216098
	normal mortality/aging	J:216098
Sostdc1^tm2Myan/Sostdc1^tm2Myan Not Specified	abnormal tooth morphology	J:152884
Sostdc1^tm2Snd/Sostdc1^tm2Snd involves: 129S/SvEv	abnormal bone mineralization	J:216098
	increased bone mineral density	J:216098
	preweaning lethality, incomplete penetrance	J:216098

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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