Serpinb1a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Serpinb1a
serine (or cysteine) peptidase inhibitor, clade B, member 1a
MGI:1913472

13 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Serpinb1a^tm1.1Cben/Serpinb1a^tm1.1Cben 129S6/SvEvTac-Serpinb1a^tm1.1Cben	abnormal chemokine secretion	J:125918
	abnormal circulating cytokine level	J:125918
	abnormal neutrophil physiology	J:125918
	abnormal surfactant physiology	J:125918
	decreased neutrophil cell number	J:125918
	impaired neutrophil chemotaxis	J:125918
	increased interleukin-1 beta secretion	J:125918
	increased susceptibility to bacterial infection	J:125918
	increased susceptibility to bacterial infection induced morbidity/mortality	J:125918
	increased tumor necrosis factor secretion	J:125918
	lung inflammation	J:125918
	sepsis	J:125918
Serpinb1a^tm1.1Cben/Serpinb1a^tm1.1Cben involves: 129S6/SvEvTac	increased apoptosis	J:217636

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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