Exosc3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Exosc3
exosome component 3
MGI:1913612

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Exosc3^{tm1.1(KOMP)Vlcg}/Exosc3⁺ C57BL/6N-Exosc3^{tm1.1(KOMP)Vlcg}/Ucd	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	enlarged heart	J:211773
	increased fasting circulating glucose level	J:211773
	polycystic kidney	J:211773
Exosc3^{tm1.1(KOMP)Vlcg}/Exosc3^{tm1.1(KOMP)Vlcg} C57BL/6N-Exosc3^{tm1.1(KOMP)Vlcg}/Ucd	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Exosc3^tm2.1Vlcg/Exosc3^tm2.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:200671

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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