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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Aptx
aprataxin
MGI:1913658
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Aptxtm1Pmc/Aptx+
Atmtm2.1Mfgc/Atmtm2.1Mfgc
involves: 129 * C57BL/6 		decreased survivor rate J:316365
increased thymoma incidence J:316365
Aptxtm1Pmc/Aptxtm1Pmc
Atmtm2.1Mfgc/Atmtm2.1Mfgc
involves: 129 * C57BL/6 		abnormal CD4-positive helper T cell morphology J:316365
abnormal gait J:316365
abnormal motor coordination/balance J:316365
abnormal nervous system electrophysiology J:316365
abnormal Purkinje cell dendrite morphology J:316365
abnormal Purkinje cell morphology J:316365
abnormal synaptic physiology J:316365
abnormal T cell differentiation J:316365
ataxia J:316365
cerebellum atrophy J:316365
decreased body weight J:316365
decreased survivor rate J:316365
decreased T cell number J:316365
impaired coordination J:316365
impaired neuron physiology J:316365
impaired righting response J:316365
increased CD8-positive, alpha-beta T cell number J:316365
increased excitatory postsynaptic current frequency J:316365
increased thymoma incidence J:316365
neurodegeneration J:316365
slow postnatal weight gain J:316365
thin cerebellar molecular layer J:316365
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory