Fis1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fis1
fission, mitochondrial 1
MGI:1913687

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fis1^tm1.1Itl/Fis1^tm1.1Itl Tg(Ckmm-cre)5Khn/0 involves: C57BL/6NTac * FVB	abnormal mitochondrial crista morphology	J:290485
	abnormal mitochondrial physiology	J:290485
	abnormal skeletal muscle morphology	J:290485
	abnormal Z line morphology	J:290485
	impaired exercise endurance	J:290485
	increased body temperature	J:290485
	increased circulating interferon-beta level	J:290485
	increased circulating interleukin-6 level	J:290485
	increased circulating interleukin-12b level	J:290485
	increased circulating interleukin-13 level	J:290485
	increased mitochondrial size	J:290485
Fis1^{tm1b(EUCOMM)Hmgu}/Fis1⁺ C57BL/6N-Fis1^{tm1b(EUCOMM)Hmgu}/Ieg	increased circulating bilirubin level	J:211773
Fis1^{tm1b(EUCOMM)Hmgu}/Fis1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Fis1^{tm1b(EUCOMM)Hmgu}/Ieg	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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