Fis1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fis1
fission, mitochondrial 1
MGI:1913687

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fis1^tm1.1Itl/Fis1^tm1.1Itl Tg(CAG-EGFP/Map1lc3b)53Nmz/0 Tg(Ckmm-cre)5Khn/0 involves: C57BL/6NCrlj * C57BL/6NTac * DBA/2 * FVB	abnormal autophagy	J:290485
Fis1^tm1Dcc/Fis1^tm1.1Dcc Gt(ROSA)26Sor^{tm1.1(CAG-COX8A/Dendra2)Dcc}/Gt(ROSA)26Sor⁺ Tg(Stra8-icre)1Reb/0 involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ	abnormal spermatid morphology	J:309044
	azoospermia	J:309044
	decreased testis weight	J:309044
	impaired autophagy	J:309044
	increased male germ cell apoptosis	J:309044
	increased mitochondrial number	J:309044
	multinucleated giant male germ cells	J:309044
	small testis	J:309044

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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