Acot11 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acot11
acyl-CoA thioesterase 11
MGI:1913736

25 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Acot11^tm1Deco/Acot11^tm1Deco involves: 129S6/SvEvTac * C57BL/6	abnormal brown adipose tissue morphology	J:182660
	abnormal brown adipose tissue physiology	J:182660
	abnormal brown adipose tissue thermogenesis	J:182660
	abnormal brown fat cell morphology	J:182660
	normal behavior/neurological phenotype	J:182660
	decreased brown fat cell lipid droplet size	J:182660
	decreased circulating cholesterol level	J:182660
	decreased circulating glucose level	J:182660
	decreased circulating HDL cholesterol level	J:182660
	decreased inflammatory response	J:182660
	decreased lean body mass	J:182660
	decreased physiological sensitivity to xenobiotic	J:182660
	decreased susceptibility to diet-induced hepatic steatosis	J:182660
	decreased susceptibility to diet-induced obesity	J:182660
	normal homeostasis/metabolism phenotype	J:182660
	improved glucose tolerance	J:182660
	increased adipocyte glucose uptake	J:182660
	increased brown adipose tissue amount	J:182660
	increased circulating triglyceride level	J:182660
	increased energy expenditure	J:182660
	increased fatty acid oxidation	J:182660
	increased fatty acids level	J:182660
	increased food intake	J:182660
	increased oxygen consumption	J:182660
	increased respiratory quotient	J:182660

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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