Exosc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Exosc1
exosome component 1
MGI:1913833

21 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Exosc1^em1(IMPC)J/Exosc1⁺ C57BL/6NJ-Exosc1^em1(IMPC)J/Mmjax	abnormal coat/ hair morphology	J:211773
Exosc1^em1(IMPC)J/Exosc1⁺ C57BL/6NJ-Exosc1^em1(IMPC)J/Mmjax	decreased heart rate	J:211773
Exosc1^em1(IMPC)J/Exosc1^em1(IMPC)J C57BL/6NJ-Exosc1^em1(IMPC)J/Mmjax	abnormal egg cylinder morphology	J:343201
	abnormal embryo morphology	J:279207
	abnormal embryonic epiblast morphology	J:279207, J:343201
	abnormal embryonic tissue morphology	J:343201
	abnormal visceral endoderm morphology	J:343201
	abnormal visceral endoderm physiology	J:343201
	absent amniotic cavity	J:343201
	absent ectoplacental cavity	J:343201
	absent extraembryonic coelom	J:343201
	absent mesoderm	J:343201
	decreased embryo size	J:279207, J:343201
	embryonic growth arrest	J:343201
	embryonic growth retardation	J:343201
	embryonic lethality between implantation and somite formation, incomplete penetrance	J:279207
	embryonic lethality prior to organogenesis, complete penetrance	J:343201
	failure of primitive streak formation	J:343201
	failure to gastrulate	J:279207, J:343201
	increased embryonic epiblast cell apoptosis	J:279207, J:343201
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24