Mad2l1bp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mad2l1bp
MAD2L1 binding protein
MGI:1913841

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mad2l1bp^tm1.1Itl/Mad2l1bp^tm1.1Itl Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * C57BL/6NTac	abnormal endocytosis	J:234643
	abnormal enzyme/coenzyme activity	J:234643
	abnormal hepatocyte physiology	J:234643
	abnormal liver physiology	J:234643
	aneuploidy	J:234643
	decreased liver glycogen level	J:234643
	decreased liver triglyceride level	J:234643
	hyperglycemia	J:234643
	impaired glucose tolerance	J:234643
	increased circulating insulin level	J:234643
	increased circulating triglyceride level	J:234643
	insulin resistance	J:234643
	normal mortality/aging	J:234643
Mad2l1bp^tm1.2Itl/Mad2l1bp^tm1.2Itl involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac	abnormal adipose tissue development	J:234643
	abnormal hepatocyte morphology	J:234643
	abnormal mitosis	J:234643
	aneuploidy	J:234643
	decreased adipocyte glucose uptake	J:234643
	decreased birth body size	J:234643
	decreased fetal size	J:234643
	decreased fibroblast proliferation	J:234643
	decreased liver glycogen level	J:234643
	fetal growth retardation	J:234643
	increased fibroblast apoptosis	J:234643
	increased mitotic index	J:234643
	normal muscle phenotype	J:234643
	neonatal lethality, complete penetrance	J:234643
	polyploidy	J:234643
	postnatal growth retardation	J:234643

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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