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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atg4b
autophagy related 4B, cysteine peptidase
MGI:1913865
33 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atg4bGt(A029E06)Wrst/Atg4bGt(A029E06)Wrst
involves: 129S2/SvPas * C57BL/6 		abnormal lipid homeostasis J:163712
abnormal otolith morphology J:163712
abnormal utricle morphology J:163712
abnormal vestibular saccular macula morphology J:163712
absent otoliths J:163712
circling J:163712
enlarged otoliths J:163712
head tilt J:163712
impaired autophagy J:163712
impaired coordination J:163712
impaired swimming J:163712
normal nervous system phenotype J:163712
Atg4bGt(OST264114)Lex/Atg4bGt(OST264114)Lex
involves: 129S5/SvEvBrd * C57BL/6J 		abnormal cerebellum deep nucleus morphology J:186046
abnormal motor learning J:186046
impaired coordination J:186046
normal nervous system phenotype J:186046
preweaning lethality, incomplete penetrance J:186046
Atg4btm1b(EUCOMM)Hmgu/Atg4btm1b(EUCOMM)Hmgu
C57BL/6N-Atg4btm1b(EUCOMM)Hmgu/H 		abnormal retina morphology J:211773
abnormal tooth morphology J:211773
cataract J:211773
decreased circulating cholesterol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased lean body mass J:211773
decreased prepulse inhibition J:211773
increased circulating alanine transaminase level J:211773
increased circulating alkaline phosphatase level J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased mean platelet volume J:211773
increased red blood cell distribution width J:211773
limb grasping J:211773
short tibia J:211773
thrombocytopenia J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory