Dph6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dph6
diphthamine biosynthesis 6
MGI:1913882

35 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Dph6^{tm1a(KOMP)Wtsi}/Dph6^{tm1a(KOMP)Wtsi} C57BL/6N-Dph6^{tm1a(KOMP)Wtsi}/Wtsi	abnormal coat/hair pigmentation	J:211773
	decreased body length	J:211773
	decreased CD8-positive, alpha-beta T cell number	J:211773
	decreased CD8-positive, naive alpha-beta T cell number	J:211773
	decreased effector memory CD8-positive, alpha-beta T cell number	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased Ly6C-positive mature NK cell number	J:211773
	decreased mature B cell number	J:211773
	decreased NK T cell number	J:211773
	decreased T-helper cell number	J:211773
	increased blood urea nitrogen level	J:211773
	increased CD4-positive, alpha-beta memory T cell number	J:211773
	increased CD4-positive, alpha-beta T cell number	J:211773
	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
	increased CD5-positive gamma-delta T cell number	J:211773
	increased CD11b-low dendritic cell number	J:211773
	increased circulating creatinine level	J:211773
	increased circulating magnesium level	J:211773
	increased dendritic cell number	J:211773
	increased effector memory T-helper cell number	J:211773
	increased gamma-delta T cell number	J:211773
	increased granulocyte number	J:211773
	increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
	increased KLRG1-positive T-helper cell number	J:211773
	increased marginal zone B cell number	J:211773
	increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
	increased memory-marker CD4-negative NK T cell number	J:211773
	increased memory-marker gamma-delta T cell number	J:211773
	increased monocyte cell number	J:211773
	increased plasma cell number	J:211773
	increased plasmacytoid dendritic cell number	J:211773
	increased red blood cell distribution width	J:211773
	vertebral transformation	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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