Lrrk2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrrk2
leucine-rich repeat kinase 2
MGI:1913975

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lrrk2^tm1.1Cai/Lrrk2⁺ Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-SNCAA53T)E2Cai/0 involves: 129X1/SvJ C57BL/6	abnormal nervous system morphology	J:156512
	abnormal neuron morphology	J:156512
	abnormal striatum morphology	J:156512
	astrocytosis	J:156512
	microgliosis	J:156512
	neurodegeneration	J:156512
Lrrk2^tm1.1Cai/Lrrk2^tm1.1Cai Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-SNCAA53T)E2Cai/0 involves: 129X1/SvJ C57BL/6	normal nervous system phenotype	J:156512

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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