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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lztr1
leucine-zipper-like transcriptional regulator, 1
MGI:1914113
37 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lztr1em1Tumg/Lztr1+
C57BL/6J-Lztr1em1Tumg
cardiac hypertrophy J:361054
Lztr1em1Tumg/Lztr1em1Tumg
C57BL/6J-Lztr1em1Tumg
subcutaneous hemorrhage J:361054
Lztr1em2Tumg/Lztr1+
C57BL/6J-Lztr1em2Tumg
abnormal cranium morphology J:361054
abnormal kidney morphology J:361054
abnormal lymphatic vessel morphology J:361054
cardiac hypertrophy J:361054
decreased body length J:361054
decreased body weight J:361054
decreased cranium length J:361054
decreased survivor rate J:361054
enlarged spleen J:361054
extramedullary hematopoiesis J:361054
hydrops fetalis J:361054
increased heart weight J:361054
increased inner canthal distance J:361054
increased kidney weight J:361054
ocular hypertelorism J:361054
premature death J:361054
prenatal lethality, incomplete penetrance J:361054
short facial bone J:361054
short frontal bone J:361054
short nasal bone J:361054
small cranium J:361054
subcutaneous hemorrhage J:361054
Lztr1em2Tumg/Lztr1em2Tumg
C57BL/6J-Lztr1em2Tumg
abnormal lymphatic vessel morphology J:361054
lethality throughout fetal growth and development, complete penetrance J:361054
Lztr1tm1a(EUCOMM)Wtsi/Lztr1+
C57BL/6N-Lztr1tm1a(EUCOMM)Wtsi/Wtsi
abnormal cranium morphology J:211773
abnormal snout morphology J:211773
increased red blood cell distribution width J:211773
Lztr1tm1a(EUCOMM)Wtsi/Lztr1+
involves: C57BL/6N
abnormal facial morphology J:268690
abnormal heart echocardiography feature J:268690
broad nasal bone J:268690
cardiac hypertrophy J:268690
decreased body weight J:268690
decreased cardiac muscle contractility J:268690
decreased cranium height J:268690
increased cardiac stroke volume J:268690
increased cell proliferation J:268690
increased cranium width J:268690
increased myocardial fiber size J:268690
premature death J:268690
short parietal bone J:268690
Lztr1tm1a(EUCOMM)Wtsi/Lztr1tm1a(EUCOMM)Wtsi
C57BL/6N-Lztr1tm1a(EUCOMM)Wtsi/Wtsi
preweaning lethality, complete penetrance J:211773
Lztr1tm1a(EUCOMM)Wtsi/Lztr1tm1a(EUCOMM)Wtsi
involves: C57BL/6N
lethality during fetal growth through weaning J:268690

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory