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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mfsd1
major facilitator superfamily domain containing 1
MGI:1914118
30 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mfsd1em1(IMPC)Tcp/Mfsd1+
C57BL/6N-Mfsd1em1(IMPC)Tcp/Tcp 		anophthalmia J:211773
enlarged lymph nodes J:211773
Mfsd1em1(IMPC)Tcp/Mfsd1em1(IMPC)Tcp
C57BL/6N-Mfsd1em1(IMPC)Tcp/Tcp 		abnormal eye morphology J:211773
abnormal liver morphology J:211773
abnormal sternum morphology J:211773
decreased circulating triglyceride level J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating bilirubin level J:211773
increased mean platelet volume J:211773
increased neutrophil cell number J:211773
increased red blood cell distribution width J:211773
persistence of hyaloid vascular system J:211773
preweaning lethality, incomplete penetrance J:211773
small testis J:211773
thrombocytopenia J:211773
Mfsd1tm1a(KOMP)Wtsi/Mfsd1tm1a(KOMP)Wtsi
involves: C57BL/6N 		abnormal hepatocyte morphology J:280713
abnormal liver morphology J:280713
abnormal liver parenchyma morphology J:280713
abnormal liver perisinusoidal space morphology J:280713
abnormal liver sinusoid morphology J:280713
abnormal liver sinusoidal endothelial cell morphology J:280713
abnormal liver vasculature morphology J:280713
decreased body weight J:280713
enlarged spleen J:280713
increased circulating alanine transaminase level J:280713
increased circulating aspartate transaminase level J:280713
increased circulating glutamate dehydrogenase level J:280713
increased liver tumor incidence J:280713
liver fibrosis J:280713
Mfsd1tm1d(KOMP)Wtsi/Mfsd1tm1d(KOMP)Wtsi
involves: C57BL/6N 		abnormal liver morphology J:280713
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory