About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mfsd1
major facilitator superfamily domain containing 1
MGI:1914118
30 phenotypes from 3 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Mfsd1em1(IMPC)Tcp/Mfsd1+
C57BL/6N-Mfsd1em1(IMPC)Tcp/Tcp 		anophthalmia J:211773
enlarged lymph nodes J:211773
Mfsd1em1(IMPC)Tcp/Mfsd1em1(IMPC)Tcp
C57BL/6N-Mfsd1em1(IMPC)Tcp/Tcp 		abnormal eye morphology J:211773
abnormal liver morphology J:211773
abnormal sternum morphology J:211773
decreased circulating triglyceride level J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating bilirubin level J:211773
increased mean platelet volume J:211773
increased neutrophil cell number J:211773
increased red blood cell distribution width J:211773
persistence of hyaloid vascular system J:211773
preweaning lethality, incomplete penetrance J:211773
small testis J:211773
thrombocytopenia J:211773
Mfsd1tm1a(KOMP)Wtsi/Mfsd1tm1a(KOMP)Wtsi
involves: C57BL/6N 		abnormal hepatocyte morphology J:280713
abnormal liver morphology J:280713
abnormal liver parenchyma morphology J:280713
abnormal liver perisinusoidal space morphology J:280713
abnormal liver sinusoid morphology J:280713
abnormal liver sinusoidal endothelial cell morphology J:280713
abnormal liver vasculature morphology J:280713
decreased body weight J:280713
enlarged spleen J:280713
increased circulating alanine transaminase level J:280713
increased circulating aspartate transaminase level J:280713
increased circulating glutamate dehydrogenase level J:280713
increased liver tumor incidence J:280713
liver fibrosis J:280713
Mfsd1tm1d(KOMP)Wtsi/Mfsd1tm1d(KOMP)Wtsi
involves: C57BL/6N 		abnormal liver morphology J:280713
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory