Rnf128 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnf128
ring finger protein 128
MGI:1914139

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Foxp3^tm2Ayr/Foxp3⁺ Rnf128^tm1Cdon/Rnf128^tm1Cdon involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal regulatory T cell physiology	J:160681
Rnf128^tm1.1Flv/Rnf128^tm1.1Flv Tg(TcraTcrb)425Cbn/0 involves: 129S6/SvEvTac * BALB/c * C57BL/6	abnormal peripheral T cell anergy	J:153216
	decreased T cell proliferation	J:153216
	increased circulating interleukin-2 level	J:153216
Rnf128^tm1.1Flv/Y Tg(TcraTcrb)425Cbn/0 involves: 129S6/SvEvTac * BALB/c * C57BL/6	abnormal peripheral T cell anergy	J:153216
	decreased T cell proliferation	J:153216
	increased circulating interleukin-2 level	J:153216
Rnf128^tm1Cdon/Rnf128^tm1Cdon Tg(TcraTcrb)425Cbn/0 involves: 129 * BALB/c * C57BL/6	abnormal immune tolerance	J:160681
	increased interferon-gamma secretion	J:160681
	increased interleukin-2 secretion	J:160681
	increased splenocyte proliferation	J:160681

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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