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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Chordc1
cysteine and histidine rich domain containing 1
MGI:1914167
35 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Chordc1em1(IMPC)Mbp/Chordc1+
C57BL/6N-Chordc1em1(IMPC)Mbp/MbpMmucd 		abnormal kidney morphology J:211773
abnormal neural tube morphology J:211773
abnormal retina morphology J:211773
abnormal skin morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
small kidney J:211773
Chordc1em1(IMPC)Mbp/Chordc1em1(IMPC)Mbp
C57BL/6N-Chordc1em1(IMPC)Mbp/MbpMmucd 		embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Chordc1tm1Mbra/Chordc1+
involves: 129 * C57BL/6 		abnormal bone marrow cell morphology/development J:222040
abnormal centrosome morphology J:222040
abnormal myelopoiesis J:222040
abnormal spleen morphology J:222040
anemia J:222040
anisocytosis J:222040
bradykinesia J:222040
decreased hemoglobin content J:222040
enlarged liver J:222040
enlarged spleen J:222040
hunched posture J:222040
increased chronic myelocytic leukemia incidence J:222040
increased leukocyte cell number J:222040
increased myeloid cell number J:222040
increased myeloid cell number in bone marrow J:222040
increased nucleated erythrocyte cell number J:222040
premature death J:222040
reticulocytosis J:222040
weight loss J:222040
Chordc1tm1Mbra/Chordc1+
Not Specified 		increased incidence of tumors by chemical induction J:159109
Chordc1tm1Mbra/Chordc1tm1Mbra
Not Specified 		abnormal inner cell mass apoptosis J:159109
abnormal trophoblast giant cell proliferation J:159109
absent inner cell mass proliferation J:159109
embryonic lethality, complete penetrance J:159109
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory