Dusp26 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dusp26
dual specificity phosphatase 26
MGI:1914209

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dusp26^em1Jhxia/Dusp26^em1Jhxia Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA	abnormal liver morphology	J:279111
	decreased liver glycogen level	J:279111
	impaired glucose tolerance	J:279111
	increased circulating alanine transaminase level	J:279111
	increased circulating aspartate transaminase level	J:279111
	increased circulating glucose level	J:279111
	increased fasting circulating glucose level	J:279111
	increased liver cholesterol level	J:279111
	increased liver free fatty acids level	J:279111
	increased liver triglyceride level	J:279111
	increased liver weight	J:279111
	increased susceptibility to diet-induced obesity	J:279111
	insulin resistance	J:279111
	liver fibrosis	J:279111
Dusp26^{tm1a(KOMP)Wtsi}/Dusp26^{tm1a(KOMP)Wtsi} C57BL/6N-Dusp26^{tm1a(KOMP)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating LDL cholesterol level	J:175295
	decreased circulating magnesium level	J:175295
	decreased circulating total protein level	J:175295
	decreased lean body mass	J:175295
	increased lean body mass	J:175295

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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